우(牛)심근조직의 mitochondria에서 cytochrome-c-oxidase의 형성과 변화 (The Formation and Change of Cytochrome-c-oxidase in the Mitochondria of the Bovine Cardiac Muscle)

서지정보

· 발행기관 : 한국현미경학회
· 수록지 정보 : Applied Microscopy / 38권 / 2호 / 125 ~ 133페이지
· 저자명 : 김인선

초록

Cytochrome-c-oxidase in mitochondria membrane is one of the most important factors for energy generation in the
cell. As well as it is electron transfer enzyme, it is also heavily related to the apoptosis and other pathologic conditions.
Meanwhile, porin is a protein located in inner and outer membranes of mitochondria, which is assumed to be functionally
correlated with cytochrome-c-oxidase. It functions as forming electron transfer chain and conveying ATP. Therefore,
using the immune-microscopy, It compared the distribution of cytochrome-c-oxidase and porin to figure out the
formation and changes on cytochrome-c-oxidase in mitochondrial cristae.
The sarcroplasm of cardic muscle tissue has many mitochondria. They are classified into two groups: the mitochondria
with many cytochrome-c-oxidase and the mitochondria with only porins. The mitochondria with porins had few
cytochrome-c-oxidases in their membrane; in contrast, the other mitochondria with rich cytochrome-c-oxidase had few
porins in their walls. In addition, according to the location of the tissue in bovine heart, distribution of those kind of
mitochondria had been clearly separated. As a result, it could be assumed that immature mitochondria has many porins to
transfer the protein materials from sarcroplasm through the porins, and they made cytochrome-c-oxidase until it is
enough, and then they decreased the porin and maintained minimum number of the porin.

영어초록

Cytochrome-c-oxidase in mitochondria membrane is one of the most important factors for energy generation in the
cell. As well as it is electron transfer enzyme, it is also heavily related to the apoptosis and other pathologic conditions.
Meanwhile, porin is a protein located in inner and outer membranes of mitochondria, which is assumed to be functionally
correlated with cytochrome-c-oxidase. It functions as forming electron transfer chain and conveying ATP. Therefore,
using the immune-microscopy, It compared the distribution of cytochrome-c-oxidase and porin to figure out the
formation and changes on cytochrome-c-oxidase in mitochondrial cristae.
The sarcroplasm of cardic muscle tissue has many mitochondria. They are classified into two groups: the mitochondria
with many cytochrome-c-oxidase and the mitochondria with only porins. The mitochondria with porins had few
cytochrome-c-oxidases in their membrane; in contrast, the other mitochondria with rich cytochrome-c-oxidase had few
porins in their walls. In addition, according to the location of the tissue in bovine heart, distribution of those kind of
mitochondria had been clearly separated. As a result, it could be assumed that immature mitochondria has many porins to
transfer the protein materials from sarcroplasm through the porins, and they made cytochrome-c-oxidase until it is
enough, and then they decreased the porin and maintained minimum number of the porin.

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