베체트병에서 뼈신티그래피를 통한 관절 침범의 평가 (Evaluation of the Articular Involvement of Behçet's Disease Via Bone Scintigraphy)

서지정보

· 발행기관 : 대한피부과학회
· 수록지 정보 : 대한피부과학회지 / 47권 / 1호 / 30 ~ 35페이지
· 저자명 : 한은천, 오상호, 방동식

초록

Background: Behçet's disease (BD) is a chronic relapsing inflammatory disease that involves various organ systems.
Articular involvement was reported to be present in approximately 50% of Korean BD patients. The joint symptoms
of BD patients have usually been described as intermittent, self-limiting and non-erosive, and they are mostly
monoarticular and oligoarticular arthritis.
Objective: The purpose of our investigations was to evaluate the usefulness of bone scintigraphy for detecting the
articular involvement of BD.
Methods: We reviewed the medical records, laboratory findings and bone scintigraphy findings of 89 patients who
were diagnosed with BD from January 2005 to June 2007.
Results: Of the 89 BD patients, 14 patients were male and 75 patients were female with a mean age of 43.92±8.49
yr. The most frequently involved site on bone scintigraphy was the wrist (44.9%) with the decreasing order of
frequency as follows: the feet (39.3%), the hands (25.8%), the knee (24.7%), the sacroiliac joint (22.4%), the
shoulder (18%), the ankle (16.9%), the hip (12.6%), the spine (10%) and the elbow (3%). The pattern of
involvement, which was defined as the number of joints showing hot uptake on the bone scintigraphy at one episode
of arthropathy, was monoarticular in 5.6%, oligoarticular in 44.9%, polyarticular in 38.2% and there was no uptake
in 11.2%. Among 130 joints, 63.1% of the joints showed close correlation between the clinical symptoms and the
bone scintigraphy uptake.
Conclusion: We suggest that bone scintigraphy can be a useful tool to determine the presence and site of articular
involvement. However, more studies are needed to exclude non-specific bone scintigraphy uptake and to determine the
correlation between clinical symptoms and the bone scintigraphy findings.

영어초록

Background: Behçet's disease (BD) is a chronic relapsing inflammatory disease that involves various organ systems.
Articular involvement was reported to be present in approximately 50% of Korean BD patients. The joint symptoms
of BD patients have usually been described as intermittent, self-limiting and non-erosive, and they are mostly
monoarticular and oligoarticular arthritis.
Objective: The purpose of our investigations was to evaluate the usefulness of bone scintigraphy for detecting the
articular involvement of BD.
Methods: We reviewed the medical records, laboratory findings and bone scintigraphy findings of 89 patients who
were diagnosed with BD from January 2005 to June 2007.
Results: Of the 89 BD patients, 14 patients were male and 75 patients were female with a mean age of 43.92±8.49
yr. The most frequently involved site on bone scintigraphy was the wrist (44.9%) with the decreasing order of
frequency as follows: the feet (39.3%), the hands (25.8%), the knee (24.7%), the sacroiliac joint (22.4%), the
shoulder (18%), the ankle (16.9%), the hip (12.6%), the spine (10%) and the elbow (3%). The pattern of
involvement, which was defined as the number of joints showing hot uptake on the bone scintigraphy at one episode
of arthropathy, was monoarticular in 5.6%, oligoarticular in 44.9%, polyarticular in 38.2% and there was no uptake
in 11.2%. Among 130 joints, 63.1% of the joints showed close correlation between the clinical symptoms and the
bone scintigraphy uptake.
Conclusion: We suggest that bone scintigraphy can be a useful tool to determine the presence and site of articular
involvement. However, more studies are needed to exclude non-specific bone scintigraphy uptake and to determine the
correlation between clinical symptoms and the bone scintigraphy findings.

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