고지방 식이를 섭취한 흰쥐에서 발효 삼정환의 항비만 효과 (Anti-Obesity Effects of Fermented Samjung-hwan in High Fat Diet Rats)

서지정보

· 발행기관 : 한방비만학회
· 수록지 정보 : 한방비만학회지 / 13권 / 1호 / 17 ~ 23페이지
· 저자명 : 송미영, 보세, 김호준

초록

Objectives: This study was performed to evaluate the effects of fermented Samjung-hwan (SJH)extracts on weight, serum lipids and blood glucose.
Methods: SJH was fermented using three different probiotic bacterial strains (Lactobacillusplantarum [LP], Leuconostoc mesenteroides [LM], Bifidobacterium longum [BL]) separately.
Thirty-six rats were divided into normal, control (high fat diet), SJH-UF (high fatdiet+unfermented SJH 200 mg/kg), SJH-LP (high fat diet+LP fermented SJH 200 mg/kg),SJH-LM (high fat diet+LM fermented SJH 200 mg/kg) and SJH-BL (high fat diet+BLfermented SJH 200 mg/kg). For 8 weeks later, we examined body weight, total cholesterol,high-density lipoprotein (HDL)-cholesterol and blood glucose.
Results: The control group showed significantly increased weight gain compared with normalgroup and SJH-LP and BL groups had less weight gain than control group, significantly. In the lipidserum tests, control group showed significantly increased total cholesterol levels compared withnormal group and only SJH-LP represented decreased total cholesterol levels compared withcontrol group. However there was no significant change in the HDL-cholesteol levels. In the bloodglucose tests, that of control group significantly incereased more than that of normal group, SJH-BL showed significantly decreased blood glucose levels compared with control group.
Conclusions: SJH-LP,SJH-BL showed weight control effect, SJH-LP decreased TC and SJH-BL reduced blood glucose.

영어초록

Objectives: This study was performed to evaluate the effects of fermented Samjung-hwan (SJH)extracts on weight, serum lipids and blood glucose.
Methods: SJH was fermented using three different probiotic bacterial strains (Lactobacillusplantarum [LP], Leuconostoc mesenteroides [LM], Bifidobacterium longum [BL]) separately.
Thirty-six rats were divided into normal, control (high fat diet), SJH-UF (high fatdiet+unfermented SJH 200 mg/kg), SJH-LP (high fat diet+LP fermented SJH 200 mg/kg),SJH-LM (high fat diet+LM fermented SJH 200 mg/kg) and SJH-BL (high fat diet+BLfermented SJH 200 mg/kg). For 8 weeks later, we examined body weight, total cholesterol,high-density lipoprotein (HDL)-cholesterol and blood glucose.
Results: The control group showed significantly increased weight gain compared with normalgroup and SJH-LP and BL groups had less weight gain than control group, significantly. In the lipidserum tests, control group showed significantly increased total cholesterol levels compared withnormal group and only SJH-LP represented decreased total cholesterol levels compared withcontrol group. However there was no significant change in the HDL-cholesteol levels. In the bloodglucose tests, that of control group significantly incereased more than that of normal group, SJH-BL showed significantly decreased blood glucose levels compared with control group.
Conclusions: SJH-LP,SJH-BL showed weight control effect, SJH-LP decreased TC and SJH-BL reduced blood glucose.

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