일개 대학병원 응급의료센터로 내원한 쯔쯔가무시병의 임상양상 (Clinical Features of Tsutsugamushi Disease in the Emergency Department)

서지정보

· 발행기관 : 대한응급의학회
· 수록지 정보 : 대한응급의학회지 / 20권 / 5호 / 569 ~ 576페이지
· 저자명 : 이재영, 도병수, 이삼범

초록

Purpose: Many of the febrile diseases developing in Korea
during the autumn are tsutsugamushi disease. The
pathogen of the disease is rickettsia of oriental tsutsugamushi.
The aim of this research was to help in the early
diagnosis and treatment by analyzing the clinical features of
patients with tsutsugamushi disease and the factors affecting
the duration of antibiotic use and admission.
Methods: A total of 177 patients diagnosed with tsutsugamushi
disease who visited the emergency department
between 2004 and 2008 were included. We retrospectively
reviewed the medical records on OCS by comparing the
relationship between clinical features and the duration of
antibiotic use or admission.
Results: In the outbreaks occurring in 2005 and 2007 no
significant clinical differences were seen. Tsutsugamushi
disease occurred in females(61.0%), the elderly (over 60
years old, 66.1%), and urban areas(56.5%). Common clinical
findings were eschar(80.8%) and skin rash(96.6%).
Complications(58.8%) included pneumonia, meningitis,
DIC, and acute renal failure. The duration of antibiotic use
was increased with increasing age over 60 years old and
with increasing body temperature. The duration of admission
was significantly correlated with the absence of eschar,
age over 40 years old, and abnormal findings of BUN/Cr,
PT/PTT, albumin.
Conclusion: In conclusion, several factors such as age,
hemoglobin, eschar, BUN/Cr, albumin and PT/PTT were
correlated with the duration of antibiotic use and admission.
Therefore, efforts to reduce them are required

영어초록

Purpose: Many of the febrile diseases developing in Korea
during the autumn are tsutsugamushi disease. The
pathogen of the disease is rickettsia of oriental tsutsugamushi.
The aim of this research was to help in the early
diagnosis and treatment by analyzing the clinical features of
patients with tsutsugamushi disease and the factors affecting
the duration of antibiotic use and admission.
Methods: A total of 177 patients diagnosed with tsutsugamushi
disease who visited the emergency department
between 2004 and 2008 were included. We retrospectively
reviewed the medical records on OCS by comparing the
relationship between clinical features and the duration of
antibiotic use or admission.
Results: In the outbreaks occurring in 2005 and 2007 no
significant clinical differences were seen. Tsutsugamushi
disease occurred in females(61.0%), the elderly (over 60
years old, 66.1%), and urban areas(56.5%). Common clinical
findings were eschar(80.8%) and skin rash(96.6%).
Complications(58.8%) included pneumonia, meningitis,
DIC, and acute renal failure. The duration of antibiotic use
was increased with increasing age over 60 years old and
with increasing body temperature. The duration of admission
was significantly correlated with the absence of eschar,
age over 40 years old, and abnormal findings of BUN/Cr,
PT/PTT, albumin.
Conclusion: In conclusion, several factors such as age,
hemoglobin, eschar, BUN/Cr, albumin and PT/PTT were
correlated with the duration of antibiotic use and admission.
Therefore, efforts to reduce them are required

참고자료

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