신경외과(NS) 수술시 자주 사용하는 약물 (지혈제 등)-NS 수술스크럽이 직접 정리한 자료

문서 내 토픽

• 1. Avitene

  솜모양의 특수 압축된 모양으로, Microfibrillar collagen이 출혈부위에 접촉되어 혈소판의 점착과 응집을 유도하는 지혈제입니다. 반투명한 엷은 황색의 경고제로, 주로 밀랍으로 만들고 연화제로 파라핀이나 바셀린, Isopropyl Palmitate를 혼합하여 기계적 압력을 제공합니다.

• 2. Bone wax

  산화재생 셀룰로오스로 만든 엷은 황색의 멸균 거즈로, 국소출혈방지용 흡수성 지혈제입니다. 수술 시 모세혈관, 정맥 및 소동맥의 출혈에 대해 결찰 등의 다른 방법이 효과적이지 않을 때 사용하는 지혈 보조제입니다.

• 3. Surgicel

  백색의 직사각형 스폰지 형태의 흡수성 지혈제로, 젤라틴이 물리적인 세망그물을 형성하여 혈액을 응고시킵니다. 상처의 출혈 정도에 따라 알맞은 용량을 사용하여 적용하며, warm saline에 담가 따뜻하게 유지하거나 건조한 상태로 사용할 수 있습니다.

• 4. Gelform

  백색의 직사각형 스폰지 형태의 흡수성 지혈제로, 젤라틴이 물리적인 세망그물을 형성하여 혈액을 응고시킵니다. 상처의 출혈 정도에 따라 알맞은 용량을 사용하여 적용하며, warm saline에 담가 따뜻하게 유지하거나 건조한 상태로 사용할 수 있습니다.

• 5. Topical thrombin

  표준화된 자연 응고 과정에서 필요한 응고인자를 제공하여 혈액 응고를 촉진하는 지혈제입니다. 건조트롬빈 500NIH vial과 멸균 식염수 5cc vial을 혼합하여 사용합니다.

• 6. Floseal

  정제젤라틴과 휴먼트롬빈으로 구성된 체내 흡수성 겔로, 눈 이외 부위의 크고 작은 출혈에 적용됩니다. 피브리노겐을 피브린으로 변화시켜 혈액 응고를 촉진합니다.

• 7. Adcon

  젤라틴과 polyglycan ester로 구성된 체내 흡수성 겔로, 신경계 또는 신경 조직 주변으로 섬유 조직이 이동하는 것을 방지하는 유착방지제입니다. laminectomy, spinal stenosis, discectomy 등에 사용되며 약 4주 내에 다시 흡수됩니다.

• 8. Regenseal

  바이오콜라겐과 피브린 등을 혼합한 콜라겐 조직보충제로, 처치 및 수술 시 결손 또는 손상된 인대, 건, 근육, 막을 보충하는 데 사용됩니다.

Easy AI와 토픽 톺아보기

• 1. Avitene

  Avitene is a collagen-based hemostatic agent that is commonly used in surgical procedures to control bleeding. It is derived from bovine collagen and acts as a physical barrier to help stop bleeding by promoting platelet aggregation and the activation of the clotting cascade. Avitene is biocompatible, biodegradable, and can be easily molded or shaped to fit the specific needs of the surgical site. It has been widely used in a variety of surgical specialties, including cardiovascular, orthopedic, and neurosurgical procedures, with generally positive outcomes. However, as with any medical device, there are potential risks and complications associated with the use of Avitene, such as foreign body reactions, infection, and the potential for allergic reactions in patients with known sensitivities to bovine-derived products. Overall, Avitene appears to be a useful and effective hemostatic agent when used appropriately and in accordance with the manufacturer's instructions.

• 2. Bone wax

  Bone wax is a surgical implant material that is commonly used to control bleeding from cut or exposed bone surfaces during surgical procedures. It is composed of beeswax, paraffin, and other additives and is applied directly to the bleeding bone surface to create a physical barrier that helps to stop the bleeding. Bone wax has been used in various surgical specialties, including orthopedics, neurosurgery, and cardiothoracic surgery, with generally positive results. However, there are some potential drawbacks and risks associated with the use of bone wax. It can interfere with bone healing and regeneration, leading to delayed union or non-union of fractures, and it has been associated with an increased risk of infection and foreign body reactions. Additionally, bone wax can be difficult to remove from the surgical site, which can complicate future procedures. Despite these potential issues, bone wax remains a widely used and effective tool for controlling bleeding from bone surfaces during surgery when used judiciously and in accordance with best practices.

• 3. Surgicel

  Surgicel is an oxidized regenerated cellulose-based hemostatic agent that is commonly used in surgical procedures to control bleeding. It is a sterile, absorbable, and non-adherent material that can be easily molded or shaped to fit the specific needs of the surgical site. Surgicel works by promoting the formation of a physical barrier that helps to stop bleeding, as well as by activating the clotting cascade and promoting platelet aggregation. It has been widely used in a variety of surgical specialties, including cardiovascular, orthopedic, and neurosurgical procedures, with generally positive outcomes. However, as with any medical device, there are potential risks and complications associated with the use of Surgicel, such as foreign body reactions, infection, and the potential for allergic reactions in patients with known sensitivities to cellulose-based products. Additionally, Surgicel can interfere with wound healing and may need to be removed from the surgical site if it is not fully absorbed. Overall, Surgicel appears to be a useful and effective hemostatic agent when used appropriately and in accordance with the manufacturer's instructions.

• 4. Gelform

  Gelform is a gelatin-based hemostatic agent that is commonly used in surgical procedures to control bleeding. It is a sterile, absorbable, and non-adherent material that can be easily molded or shaped to fit the specific needs of the surgical site. Gelform works by promoting the formation of a physical barrier that helps to stop bleeding, as well as by activating the clotting cascade and promoting platelet aggregation. It has been widely used in a variety of surgical specialties, including cardiovascular, orthopedic, and neurosurgical procedures, with generally positive outcomes. However, as with any medical device, there are potential risks and complications associated with the use of Gelform, such as foreign body reactions, infection, and the potential for allergic reactions in patients with known sensitivities to gelatin-based products. Additionally, Gelform can interfere with wound healing and may need to be removed from the surgical site if it is not fully absorbed. Overall, Gelform appears to be a useful and effective hemostatic agent when used appropriately and in accordance with the manufacturer's instructions.

• 5. Topical thrombin

  Topical thrombin is a hemostatic agent that is commonly used in surgical procedures to control bleeding. It is a purified form of the enzyme thrombin, which plays a key role in the blood clotting process. When applied to a bleeding site, topical thrombin helps to activate the clotting cascade, leading to the formation of a stable fibrin clot that helps to stop the bleeding. Topical thrombin has been used in a variety of surgical specialties, including cardiovascular, orthopedic, and neurosurgical procedures, with generally positive outcomes. It is typically easy to apply and can be used in combination with other hemostatic agents, such as collagen-based or gelatin-based products, to enhance its effectiveness. However, as with any medical device, there are potential risks and complications associated with the use of topical thrombin, such as the development of antibodies, allergic reactions, and the potential for thrombotic events. Overall, topical thrombin appears to be a useful and effective hemostatic agent when used appropriately and in accordance with the manufacturer's instructions.

• 6. Floseal

  Floseal is a hemostatic agent that is composed of a gelatin matrix and a human-derived thrombin component. It is commonly used in surgical procedures to control bleeding, particularly in areas that are difficult to access or where traditional suturing or cautery techniques may not be effective. Floseal works by creating a physical barrier to stop bleeding, while also activating the clotting cascade through the thrombin component. It has been used in a variety of surgical specialties, including cardiovascular, orthopedic, and neurosurgical procedures, with generally positive outcomes. Floseal is easy to apply and can be molded or shaped to fit the specific needs of the surgical site. However, as with any medical device, there are potential risks and complications associated with the use of Floseal, such as the development of antibodies, allergic reactions, and the potential for thrombotic events. Additionally, Floseal can interfere with wound healing and may need to be removed from the surgical site if it is not fully absorbed. Overall, Floseal appears to be a useful and effective hemostatic agent when used appropriately and in accordance with the manufacturer's instructions.

• 7. Adcon

  Adcon is a surgical adhesion barrier that is used to help prevent the formation of post-operative adhesions, which can be a common complication of many surgical procedures. It is composed of a modified hyaluronic acid and carboxymethylcellulose hydrogel that is designed to create a physical barrier between tissues, preventing them from adhering to one another during the healing process. Adcon has been used in a variety of surgical specialties, including orthopedic, general, and gynecological procedures, with generally positive outcomes. By reducing the formation of adhesions, Adcon can help to minimize the risk of complications such as chronic pain, bowel obstruction, and impaired organ function. However, as with any medical device, there are potential risks and complications associated with the use of Adcon, such as the potential for infection, foreign body reactions, and the risk of the barrier not being fully absorbed. Overall, Adcon appears to be a useful and effective adhesion barrier when used appropriately and in accordance with the manufacturer's instructions.

• 8. Regenseal

  Regenseal is a hemostatic agent that is composed of a combination of collagen and thrombin. It is designed to help control bleeding during surgical procedures by promoting the formation of a stable fibrin clot. Regenseal has been used in a variety of surgical specialties, including cardiovascular, orthopedic, and neurosurgical procedures, with generally positive outcomes. The collagen component of Regenseal helps to create a physical barrier to stop bleeding, while the thrombin component activates the clotting cascade to further enhance the hemostatic effect. Regenseal is easy to apply and can be molded or shaped to fit the specific needs of the surgical site. However, as with any medical device, there are potential risks and complications associated with the use of Regenseal, such as the development of antibodies, allergic reactions, and the potential for thrombotic events. Additionally, Regenseal can interfere with wound healing and may need to be removed from the surgical site if it is not fully absorbed. Overall, Regenseal appears to be a useful and effective hemostatic agent when used appropriately and in accordance with the manufacturer's instructions.