미생물 및 생물공학기초실험 8주차: Screening Natural Inhibitory Compounds on Melanin Biosynthesis [A+ 리포트]

소개

연세대학교 2017년 1학기 A+ 받은 리포트입니다.

실험관련 topic에 대해 많은 조사를 했기에 이 자료 하나로 충분할거에요.

목차

1. OBJECTIVES
2. EXPERIMENTAL THEORY
3. MATERIALS
4. PROCEDURE
5. RESULT
6. DISCUSSIONS/CONCLUSION
7. REFERENCES

본문내용

OBJECTIVES
In this investigation, the main objective is to understand melanin biosynthetic pathways and screen inhibitor on melanin biosynthesis.

EXPERIMENTAL THEORY
What is Melanin?
Human skin is comprises of two main layers known as Epidermis and underlying layer called Dermis. Melanocytes, which play a role in photo-protection and thermoregulation by producing melanin, can be found at the junction of Epidermis and Dermis. Here, Melanin is produced in specialized organelles called Melanosomes and two major classes of natural Melanin can be found in animals. First of all, Eumelanin (black-brown) are found in Retina of the eye and black hair in human. Also, Pheomelanin (yellow-red) can be observed in red feathers and hairs. Although melanin has a critical role in protecting the skin from UV light, overproduction can possibly lead to skin disorders such as senile lentigines, melasma, freckles and etc.

참고자료

· Experiment in Microbiology and Biochemical Engineering Laboratory Booklet –Department of Biotech. Yonsei University.
· "Hyperpigmentation." DermaMedics :: Overview and Treatment of Skin Hyperpigmentation. Web. 27 Apr. 2017. <http://www.dermamedics.com/hyperpigmentation_id60.html>.
· Pérez, Jorge Alberto Mendoza, and Tomás Alejandro FregosoAguilar."Chemistry of Natural Antioxidants and Studies Performed with Different Plants Collected in Mexico." Chemistry of Natural Antioxidants and Studies Performed with Different Plants Collected in Mexico | InTechOpen. InTech, 22 May 2013. Web. 27 Apr. 2017.