탄산음료 유발 법랑질 침식에 대한 항우식 제품의 예방 효과 (The preventive effect of commercially available anticariogenic products on enamel erosion induced by carbonated beverage in vitro)

서지정보

· 발행기관 : 대한소아치과학회
· 수록지 정보 : 대한소아치과학회지 / 37권 / 1호 / 1 ~ 12페이지
· 저자명 : 송주현, 김영재, 김정욱, 장기택, 김종철, 한세현, 이상훈

초록

본 연구는 항우식 제품인 Casein phosphopeptide-amorphous calcium phosphate(CPP-ACP)를 포함하는 치아크림,불소 바니쉬, 저농도 불소 양치액을 치아에 도포하는 것이 단시간 탄산음료에 의한 법랑질의 침식을 예방할 수 있는지 살펴보기 위해 계획되었다. 법랑질 시편에 다음과 같은 항우식 제품을 도포하였고, 인공타액에 24시간 보관한 후, 콜라에 1분 증류수에 1분씩 5회 번갈아 처리하였다.
1군: 대조군(무처치)2군: CPP-ACP 치아크림군3군: 불소 바니쉬군(1,000 ppm F)4군: 저농도 불소 양치액군(227 ppm F)5군: 불소 바니쉬 + CPP-ACP 치아크림군6군: 저농도 불소 양치액 + CPP-ACP 치아크림군미세경도와 침식깊이를 측정하였고, Quantitative light-induced fluorescence(QLF)를 이용하여 안정된 형광 격자에대한 부피 형광 변화인 ΔQ를 측정하여 무기질 감소량을 평가하였다. 6일 동안 실험을 반복하여 다음과 같은 결과를 얻었다.
1. 미세경도는 1군≤2군≤4군<6군<3군≒5군 순이었다.
2. 평균 침식깊이는 5군≒3군<6군<4군≒2군≒1군 순이었다.
3. ΔQ는 1군≒2군≤4군≤6군≤3군≒5군 순이었다. ΔQ의 감소율은 1군과 2군, 4군과 6군, 3군과 5군이 각각 유사하였다.
4. ΔQ는 미세경도와 강한 양의 상관관계를 나타냈고(r=0.96, p<0.05), 침식깊이와는 강한 음의 상관관계를 보였다(r=-0.96,p<0.05).

영어초록

The aim of this study was to evaluate the preventive effect of commercially available anticariogenic products,specifically, the tooth cream containing Casein phosphopeptide-amorphous calcium phosphate(CPP-ACP), fluoride varnish and low-level fluoride mouthrinse on enamel erosion induced by carbonated beverage in a short period of time. Enamel specimens were treated as follows and were then kept in artificial saliva for 24 hours followed by further processing by alternately soaking them in Cola beverage and in distilled water for 1 minute each five times.
Group 1: control group (no treatment)Group 2: tooth cream with CPP-ACP Group 3: fluoride varnish (1,000 ppm F)Group 4: low-level fluoride mouthrinse (227 ppm F)Group 5: fluoride varnish + tooth cream with CPP-ACP Group 6: low-level fluoride mouthrinse + tooth cream with CPP-ACP Microhardness and erosion depth were measured and the mineral loss of each specimen was evaluated by measuring the volumetric fluorescence change(ΔQ) against the stable fluorescent grid using quantitative lightinduced fluorescence(QLF). The experiment lasted for 6 days repeated each day. The results were as follows:1. The microhardness was increased as follows: Group 1≤2≤4<6<3≒5.
2. The mean erosion depth was increased as follows: Group 5≒3<6<4≒2≒1.
3. The ΔQ was increased as follows: Group 1≒2≤4≤6≤3≒5. The decrement of ΔQ was similar between group 1 and 2, group 4 and 6 and group 3 and 5.
4. The ΔQ showed positive correlation with microhardness (r=0.96, p<0.05), while it was negatively correlated to erosion depth (r=-0.96, p<0.05).

참고자료

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