피부 전이로 진단된 횡문근양 표현형을 동반한 대세포 폐암 1예 (A Case of Large Cell Lung Carcinoma with Rhabdoid Phenotype Presenting as Cutaneous Metastasis)

서지정보

· 발행기관 : 대한피부과학회
· 수록지 정보 : 대한피부과학회지 / 52권 / 4호 / 269 ~ 273페이지
· 저자명 : 서현민, 이가영, 김정인, 김윤환, 민준홍, 이승재, 박지혜, 김원석

초록

Large cell carcinoma with a rhabdoid phenotype is very rare. We report the case of a 53-year-old man who presentedwith multiple nodules on the scalp, face, and trunk. A skin biopsy revealed large cell carcinoma with a rhabdoidphenotype throughout the dermis. Tumor cells had abundant cytoplasm, eccentric nuclei, and prominent nucleoliand did not adhere to each other. Immunohistochemical tests showed positive reactions for vimentin, epithelialmembrane antigen (EMA), and thyroid transcription factor-1 (TTF-1) and weakly focal reactions for pan-CK, CK7,and p63. Imaging studies and a percutaneous lung biopsy were performed and the results were consistent with alarge cell lung carcinoma with a rhabdoid phenotype. Based on these clinical and histopathological findings, weconcluded that his condition was a cutaneous metastasis from a large cell lung carcinoma with a rhabdoidphenotype, which occurs very rarely.

영어초록

Large cell carcinoma with a rhabdoid phenotype is very rare. We report the case of a 53-year-old man who presentedwith multiple nodules on the scalp, face, and trunk. A skin biopsy revealed large cell carcinoma with a rhabdoidphenotype throughout the dermis. Tumor cells had abundant cytoplasm, eccentric nuclei, and prominent nucleoliand did not adhere to each other. Immunohistochemical tests showed positive reactions for vimentin, epithelialmembrane antigen (EMA), and thyroid transcription factor-1 (TTF-1) and weakly focal reactions for pan-CK, CK7,and p63. Imaging studies and a percutaneous lung biopsy were performed and the results were consistent with alarge cell lung carcinoma with a rhabdoid phenotype. Based on these clinical and histopathological findings, weconcluded that his condition was a cutaneous metastasis from a large cell lung carcinoma with a rhabdoidphenotype, which occurs very rarely.

참고자료

· 없음