암환자의 ABO 혈액형에 따른 암 종별 발생 빈도 (Generation Frequency of Cancer Types according to ABO Blood Type of Cancer Patient)

서지정보

· 발행기관 : 한국자연치유학회
· 수록지 정보 : Journal of Naturopathy (한국자연치유학회지) / 2권 / 1호 / 44 ~ 53페이지
· 저자명 : 홍성진, 이형환

초록

우리나라 암환자의 ABO 혈액형에 따른 암 종별 발생빈도에 관한 조사 연구를 하였다. 지역은 경기, 서울 등 수도권 지역과 전남 지역의 암 전문요양병원에서 요양을 하고 있는 암환자와 각 시·도 보건소에서 암환자로 등록되어있는 대상자 등 총 780명에 대하여 인구사회학적 특성을 조사하였고, ABO 혈액형에 따른 암의 발병빈도에 대해 교차분석 및 카이제곱 적합도 검증 등 통계적 분석을 실시하였다. 조사대상 암환자의 요양상태는 암 전문 요양기관 요양환자가 325명(41.7%), 자가 요양환자가 455명(58.3%)이었고 이 환자들에 대해 인구사회학적 특성에 대해 빈도 분석을했다. 설문에 응한 전체 780명 환자 중 암 종별로는 간암 34명(4.4%), 위암 130명(16.7%), 폐암 74명(9.5%), 대장암100명(12.8%), 유방암 240명(30.8%), 기타암(자궁암, 갑상선암, 전립선암등) 202명(25.9%)으로나타났다. ABO 혈액형별 전체 암 환자의 발생빈도는 A형이 279명(35.7%), B형은 193명(24.7%), O형은 223명(28.58%) 그리고 AB형은85명(10.9%)으로 나타났다. 이를 2011년도 우리나라 헌혈자의 ABO 혈액형 분포도와 비교분석하면 A형과 O형은 B 형과 AB형에 비하여 상대적으로 암 발생 빈도가 약간 높은 것으로 나타났다. 암종과 환자의 혈액형에 대한 교차분석결과에서는 p<.03으로 암종에 따라 혈액형별 빈도의 분포가 통계적으로 유의한 차이가 있었다. 특히 폐암에서는 A형환자의 비율이 대조군보다 높았다. 위암과 폐암, 대장암에서는 O형의 비율이 높았고, 위암의 경우 A형의 경우에서도대조군보다 발생빈도가 높았다. 유방암에서는 B형이 높은 발생 빈도를 보였다. 간암과 그 외 기타 암(백혈병, 갑상선암 등)에서 AB형 환자의 비율이 대조군보다 높았다. ABO 혈액형별 암환자의 자연치유요법 이용경험은 A형은95.8%, B형은95.6%, O형은 94.2%, AB형은 97.6%로 나타났고, 전체 환자의 95.6%가 자연치유요법을 이용하였다. 결론적으로 ABO 혈액형에따라암환자의발생위험빈도가 차이가있었으며, 암발생부위별로도 ABO 혈액형에따른발생빈도의 유의한 차이가 있었다.

영어초록

This study relates to the generation frequency of cancer type according to ABO blood type of cancer patient in Korea. The research area was capital zone of Gyeonggi and Seoul along with Jeonnam province, in which 780 cancer patients who are hospitalized in the cancer caring hospital or registered in the health center of each city and province for the visiting health care were surveyed to find out the sociodemographic characteristics according to ABO blood type and the result was analyzed with SPSS statistic program. The sociodemographic characteristics of surveyed cancer patients were as follows: men were 268(34.4%), women 512(65.6%); in their age, 30s or younger were 34(4.4%), 40s 139(17.8%), 50s 261(33.5%), 60s 189(24.2%) and 70s or older 157(20.1%), in which 50s or older were more than 70%; in the background of their main growth, metropolis were 220(28.2%), medium city 198(25.4%) and small city 362(46.4%), so those in smaller urban area were the most; in the development state when they were diagnosed as cancer, the early stage(stage I) were 303(38.8%), the middle stage(stage II) 320(41.0%) and the terminal stage(stage III) 136(17.4%), so the discovery rate in middle stage was the highest; in their care state, the patients hospitalized in the cancer care center were 325(41.7%) and those in their home 455(58.3%), so the patients cared in their home were more. Among the 780 cancer patients who have responded to the questionnaire, liver cancer patients were 34 (4.4%), stomach cancer 130(16.7%), lung cancer 74(9.5%), colon cancer 100(12.8%), breast cancer 240 (30.8%), uterine cancer 34(4.4%), thyroid cancer 49(6.3%), prostate cancer 11(1.4%) and other cancers(leukemia, pancreas cancer, esophagus cancer, brain tumor etc.) were 108(13.8%). In the generation frequency of cancer according to blood type, A-type were 279(35.7%), B-type 193(24.7%), O-type 223(28.58%) and ABtype 85(10.9%). When compared with the ABO blood type distribution of Korean blood donators in 2012, Atype patients were higher by 1.4% than reference group(34.3%); O-type were higher by 1.2% than reference group(27.4%); meanwhile, B-type were lower by 2.1% than reference group(26.8%); AB-type were lower by 0.6%. In the blood type distribution of cancer patients, 41.9% of A-type patients had the lung cancer, which was 7.6% higher than 34.3% of reference group; in case of O-type patients, the stomach cancer and the lung cancer were 33.8% respectively, which was 6.4% higher than 27.4% of reference group with the statistical significance. Meanwhile, in case of B-type patients, the breast cancer was 32.5%, which was 5.7% higher than 26.8% of reference group. In case of AB-type patients, the liver cancer was 14,7%, which was 3.3% higher than 11.4% of reference group. Furthermore, in AB-type patients, the other cancers such as leukemia and thyroid cancer except 5 typical cancers were 38.8%, which was 27.4% higher than 11.4% of reference group. So, AB-type turned out to have higher possibility for other cancers than that of 5 typical cancers. In the experience of natural therapy, A-type patients were 267(95.8%), B-type 185(95.6%), O-type 211(94.2%) and AB-type 83 (97.6%). So, 746(95.6%) of total 780 patients had the natural therapy experience. In conclusion, the frequent generation positions and the generation rate of cancers were different with the statistical significance according to ABO blood type. Among the total cancer patients, A- and O-type patients had a relatively high possibility of cancer generation than B- and AB-type patients and reference group. In the cancer type, A-type patients had higher generation rate in lung cancer and stomach cancer than reference group; O-type patients had higher rate in colon cancer, lung cancer and stomach cancer than reference group with the statistic significance. 746 (95.6%) of total 780 patients had experienced the natural therapy according to blood type.

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