국내 20세 이하 연령에서의 신종양 등록현황: 1997-2001 (Renal Tumor Registry under the Age of 20 in Korea: 1997-2001)

서지정보

· 발행기관 : 대한비뇨의학회
· 수록지 정보 : Investigative and Clinical Urology / 45권 / 4호 / 315 ~ 323페이지
· 저자명 : 대한소아비뇨기과학회, 이상돈, 김경도

초록

Purpose: To date, there has been no multi-institutional report on pediatric renal tumors in Korea. Our study was undertaken to obtain valuable demographic data for a better understanding of the biological behavior and optimal management for these tumors in patients under the age of 20 years.
Materials and Methods: The testicular tumor registry form was mailed to all 87 hospitals registered in the Korean Urology Association. The five-year medical records at each hospital were retrospectively reviewed, which included age, presentation, evaluation, treatment and outcome.
Results: 240 patients(0.1-19.7 years; ave. 3.6) were enrolled in this registry; the incidence of renal tumors was 0.33 per 100,000 population under the age of 20 years. Most patients were diagnosed with an abdominal mass before the age of 4 years. The pathological diagnoses were malignant and benign tumors in 90.4 and 9.6%, respectively. A Wilms' tumor was the most common(77.9%) malignant tumor, with a multilocular cystic nephroma(4.2%) in the most common benign tumor. 20.2% of patients were accompanied by other diseases, such as hypertension, hemihypertrophy, cryptorchidism and aniridia. The managements were as follows: surgery (16.3%), chemotherapy and/or radiotherapy after surgery(61.6%), surgery after biopsy and chemotherapy(18.7%) and others(12.5%). The results of treatment included; complete or incomplete remission(72.5%), no response or aggravation(9.6%) and unknown(16.7%). The overall metastasis rate was 24.7%. The outcomes at the last follow up(ave. 33.2 mos.) were alive, dead and unknown due to follow up loss, in 72.1, 6.7 and 21.2%, respectively.
Conclusions: These demographic data and biological behaviors for renal tumors in Korea under the age of 20 years will lead to a better understanding of these rare tumors and to the optimal therapy for these young peoples. (Korean J Urol 2004;45:315-323)

영어초록

Purpose: To date, there has been no multi-institutional report on pediatric renal tumors in Korea. Our study was undertaken to obtain valuable demographic data for a better understanding of the biological behavior and optimal management for these tumors in patients under the age of 20 years.
Materials and Methods: The testicular tumor registry form was mailed to all 87 hospitals registered in the Korean Urology Association. The five-year medical records at each hospital were retrospectively reviewed, which included age, presentation, evaluation, treatment and outcome.
Results: 240 patients(0.1-19.7 years; ave. 3.6) were enrolled in this registry; the incidence of renal tumors was 0.33 per 100,000 population under the age of 20 years. Most patients were diagnosed with an abdominal mass before the age of 4 years. The pathological diagnoses were malignant and benign tumors in 90.4 and 9.6%, respectively. A Wilms' tumor was the most common(77.9%) malignant tumor, with a multilocular cystic nephroma(4.2%) in the most common benign tumor. 20.2% of patients were accompanied by other diseases, such as hypertension, hemihypertrophy, cryptorchidism and aniridia. The managements were as follows: surgery (16.3%), chemotherapy and/or radiotherapy after surgery(61.6%), surgery after biopsy and chemotherapy(18.7%) and others(12.5%). The results of treatment included; complete or incomplete remission(72.5%), no response or aggravation(9.6%) and unknown(16.7%). The overall metastasis rate was 24.7%. The outcomes at the last follow up(ave. 33.2 mos.) were alive, dead and unknown due to follow up loss, in 72.1, 6.7 and 21.2%, respectively.
Conclusions: These demographic data and biological behaviors for renal tumors in Korea under the age of 20 years will lead to a better understanding of these rare tumors and to the optimal therapy for these young peoples. (Korean J Urol 2004;45:315-323)

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