중증 천식발작 회복 후 임상경과 - 제2보 (Clinical Outcomes after Recovery from Severe Asthma Exacerbation - the Second Report)

서지정보

· 발행기관 : 대한천식알레르기학회
· 수록지 정보 : 천식 및 알레르기 / 29권 / 1호 / 27 ~ 32페이지
· 저자명 : 정해영, 최인선, 이우진, 반희정, 이성지

초록

Background: Approximately 10% of patients with near- fatal asthma (NFA) die within a year of an attack, and close follow-up is helpful to prevent fatal events.
Objective: To investigate the clinical outcomes of acute severe asthma and whether close follow-up may help to improve clinical outcomes.
Method: Asthma patients (N=225), who were hospitalized due to severe exacerbation during the period 1998∼2006, were followed up using questionnaires or phone interviews. The 146 patients, who had regularly visited our hospital until the examination, were assigned as regular hospital visitor.
Result: Twenty-two (9.8%) of the total patients and 7 (15.9%) of 44 NFA patients died (mean follow-up period:138.9 weeks). The mortality rate was significantly lower in regular hospital visitors than in the others (total: 6.2% vs. 16.5%, P＜0.05; NFA: 3.4% vs. 40.0%, P＜0.01). The regular hospital visitors controlled their asthma better (controlled/partly controlled/uncontrolled: 75/38/33 vs. 20/ 28/31; P＜0.001), had better knowledge of asthma (9.7± 0.2 vs. 8.5±0.3, P＜0.01) and used inhaled steroid more frequently (74.7% vs. 55.7%, P＜0.001) than the others.
Conclusion: Not a few patients with acute severe asthma die after discharge from hospital. However, close follow-up and adequate asthma control seem to help in the reduction of asthma mortality.

영어초록

Background: Approximately 10% of patients with near- fatal asthma (NFA) die within a year of an attack, and close follow-up is helpful to prevent fatal events.
Objective: To investigate the clinical outcomes of acute severe asthma and whether close follow-up may help to improve clinical outcomes.
Method: Asthma patients (N=225), who were hospitalized due to severe exacerbation during the period 1998∼2006, were followed up using questionnaires or phone interviews. The 146 patients, who had regularly visited our hospital until the examination, were assigned as regular hospital visitor.
Result: Twenty-two (9.8%) of the total patients and 7 (15.9%) of 44 NFA patients died (mean follow-up period:138.9 weeks). The mortality rate was significantly lower in regular hospital visitors than in the others (total: 6.2% vs. 16.5%, P＜0.05; NFA: 3.4% vs. 40.0%, P＜0.01). The regular hospital visitors controlled their asthma better (controlled/partly controlled/uncontrolled: 75/38/33 vs. 20/ 28/31; P＜0.001), had better knowledge of asthma (9.7± 0.2 vs. 8.5±0.3, P＜0.01) and used inhaled steroid more frequently (74.7% vs. 55.7%, P＜0.001) than the others.
Conclusion: Not a few patients with acute severe asthma die after discharge from hospital. However, close follow-up and adequate asthma control seem to help in the reduction of asthma mortality.

참고자료

· 없음