간신증후군으로 오인하였던 메포르민에 의한 유산산증 1예 (A Case of Metformin-Induced Lactic Acidosis with Acute Kidney Injury Misdiagnosed as Hepatorenal Syndrome in a Cirrhosis Patient)

서지정보

· 발행기관 : 대한내과학회
· 수록지 정보 : 대한내과학회지 / 82권 / 2호 / 241 ~ 246페이지
· 저자명 : 김옥기, 옥찬영, 정지민, 이정원, 신민호, 김남호

초록

저자들은 간경화 환자에서 메포르민에 의해 발생한 유산산증 및 급성 신손상 환자를 약물 복용력이 확인되지 않아 간신증후군으로 오진하였던 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

영어초록

Metformin is a well-established drug for the treatment of type 2 diabetes mellitus. The incidence of metformin-induced lactic acidosis is low, but the estimated mortality rate is approximately 50% in cases with lactic acidosis in combination with metformin therapy. Lactic acidosis occurs most often in patients with compromised cardiac, pulmonary, hepatic, and/or renal function. Acute kidney injury is a relatively frequent problem in cirrhosis patients. Hepatorenal syndrome is a diagnosis of exclusion, making its diagnosis difficult in the clinical field. We report a case of metformin-induced lactic acidosis with acute kidney injury that was misdiagnosed as hepatorenal syndrome in a cirrhosis patient. (Korean J Med 2012;82:241-246)

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