굴피나무 추출물의 항균 활성 및 추출물을 함유한 크림의 안정성 분석 (Antibacterial Activity of Platycarya strobilacea Extract and Stability of the Extract-containing Cream)

서지정보

· 발행기관 : 한국미생물·생명공학회
· 수록지 정보 : 한국미생물·생명공학회지 / 37권 / 2호 / 170 ~ 175페이지
· 저자명 : 양희정, 김은희, 강성태, 박수남

초록

The extract of Platycarya strobilacea is known to possess a wide range of
pharmacological activities including anti-inflammatory, anti-fungal, and anti-cancer properties. We have
reported that the ethyl acetate fraction of Platycarya strobilacea (PS-ET fraction) has high potential as an antioxidant
agent (J. Soc. Cosmet. Scientists Korea 34(4) 275, 2008). In this study, antibacterial activity of the
fraction and stability of the cream containing 0.2% PS-ET fraction were investigated for the application to
cosmetics. Antibacterial activity of PS-ET fraction against various skin pathogenic bacteria (Propionibacterium
acnes, Staphylococcus aureus, and Pityrosporum ovale) was measured by minimum inhibitory concentration
(MIC). MIC values of PS-ET fraction on P. acnes, S. aureus, and P. ovale were 0.13%, 0.06% and
0.25%, respectively. The results showed that the antibacterial activity of the fraction was the highest in the S.
aureus. For the stability evaluation, pH and viscosity of the cream containing 0.2% PS-ET fraction were measured.
The results showed that pH changes of the cream containing PS-ET fraction was lower than the control
cream without PS-ET fraction. And the PS-ET fraction could repress the decrease of viscosity of the cream
against sunlight treatment. These results suggest that the fraction of Platycarya strobilacea has high potential
as bactericide against the skin pathogenic bacteria and could be added to improve the stability of cosmetic
products.

영어초록

The extract of Platycarya strobilacea is known to possess a wide range of
pharmacological activities including anti-inflammatory, anti-fungal, and anti-cancer properties. We have
reported that the ethyl acetate fraction of Platycarya strobilacea (PS-ET fraction) has high potential as an antioxidant
agent (J. Soc. Cosmet. Scientists Korea 34(4) 275, 2008). In this study, antibacterial activity of the
fraction and stability of the cream containing 0.2% PS-ET fraction were investigated for the application to
cosmetics. Antibacterial activity of PS-ET fraction against various skin pathogenic bacteria (Propionibacterium
acnes, Staphylococcus aureus, and Pityrosporum ovale) was measured by minimum inhibitory concentration
(MIC). MIC values of PS-ET fraction on P. acnes, S. aureus, and P. ovale were 0.13%, 0.06% and
0.25%, respectively. The results showed that the antibacterial activity of the fraction was the highest in the S.
aureus. For the stability evaluation, pH and viscosity of the cream containing 0.2% PS-ET fraction were measured.
The results showed that pH changes of the cream containing PS-ET fraction was lower than the control
cream without PS-ET fraction. And the PS-ET fraction could repress the decrease of viscosity of the cream
against sunlight treatment. These results suggest that the fraction of Platycarya strobilacea has high potential
as bactericide against the skin pathogenic bacteria and could be added to improve the stability of cosmetic
products.

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