임플란트 주위염 치료시 치아회분말과 치과용 연석고의 혼합 매식의 골재생 효과 (A biologic study on toothash - plaster of paris mixture with absorbable collagen membrane in the treatment of peri-implant defects)

서지정보

· 발행기관 : 대한악안면성형재건외과학회
· 수록지 정보 : Maxillofacial Plastic Reconstructive Surgery / 30권 / 2호 / 142 ~ 149페이지
· 저자명 : 최희연, 김학균, 김수관, 문성용, 김상렬, 박광범, 김용민, 임성철, 김은석, 이정훈

초록

The purpose of this study was to evaluate histomorphometrically a toothash - plaster of Paris mixture
associated with collagen membrane (Bio-Gide), regarding new bone formation in the periimplantitis
defects in dogs. Three mandibular molars were removed from 1-year-old mongrel dogs.
After 2 months of healing, 2 titanium implants with sandblasted with large grit and acid etched
(SLA) surface were installed in each side of the mandible. Experimental peri-implantitis was
induced with ligatures after successful osseointegration. Ligatures were removed after identification
of bone defect beneath the level of 5th thread of fixture on radiographic image. The mucoperiosteal
flaps were elevated and the contaminated fixtures were treated with chlorhexidine and saline. The
bone defects were assigned to one of the following treatments: no guided bone regeneration (GBR)
procedure (group 1), GBR with Bio-Oss and Bio-Gide (group 2), or GBR with toothash - plaster of
Paris mixture (TPM) and Bio-Gide (group 3). The dogs were sacrificed after 8 or 16 months. The
mean percentages of new bone formation within the limits of the 5 most coronal threads were 17.83
±10.69 (8 weeks) and 20.13±13.65 (16 weeks) in group 1, 34.25±13.32 (8 weeks) and 36.33±
14.21 (16 weeks) in group 2, and 46.33±18.39 (8 weeks) and 48.00±17.78 (16 weeks) in group 3,
respectively. The present study confirmed statistically considerable new bone formation within the
threads in group 3 compared with group 1 at 8 and 16 weeks (P<0.05). Although, data analysis did
not reveal significant differences between group 2 and 3, the latter showed better results during the
period of 8 or 16 weeks. Our findings support the effectiveness of TPM as a GBR material in the
treatment of peri-implantitis bone defect.

영어초록

The purpose of this study was to evaluate histomorphometrically a toothash - plaster of Paris mixture
associated with collagen membrane (Bio-Gide), regarding new bone formation in the periimplantitis
defects in dogs. Three mandibular molars were removed from 1-year-old mongrel dogs.
After 2 months of healing, 2 titanium implants with sandblasted with large grit and acid etched
(SLA) surface were installed in each side of the mandible. Experimental peri-implantitis was
induced with ligatures after successful osseointegration. Ligatures were removed after identification
of bone defect beneath the level of 5th thread of fixture on radiographic image. The mucoperiosteal
flaps were elevated and the contaminated fixtures were treated with chlorhexidine and saline. The
bone defects were assigned to one of the following treatments: no guided bone regeneration (GBR)
procedure (group 1), GBR with Bio-Oss and Bio-Gide (group 2), or GBR with toothash - plaster of
Paris mixture (TPM) and Bio-Gide (group 3). The dogs were sacrificed after 8 or 16 months. The
mean percentages of new bone formation within the limits of the 5 most coronal threads were 17.83
±10.69 (8 weeks) and 20.13±13.65 (16 weeks) in group 1, 34.25±13.32 (8 weeks) and 36.33±
14.21 (16 weeks) in group 2, and 46.33±18.39 (8 weeks) and 48.00±17.78 (16 weeks) in group 3,
respectively. The present study confirmed statistically considerable new bone formation within the
threads in group 3 compared with group 1 at 8 and 16 weeks (P<0.05). Although, data analysis did
not reveal significant differences between group 2 and 3, the latter showed better results during the
period of 8 or 16 weeks. Our findings support the effectiveness of TPM as a GBR material in the
treatment of peri-implantitis bone defect.

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