조기위암 치료 후 발생한 속발성 외투막세포백혈병의 증례보고

서지정보

· 발행기관 : 대한혈액학회
· 수록지 정보 : Blood Research / 43권 / 4호 / 247 ~ 252페이지
· 저자명 : 어완규, 안규정, 이우인, 임성직, 정종수

초록

We report here on a case of metachronous second primary non-Hodgkin’s lymphoma (NHL) that was diagnosed 6 years after performing subtotal gastrectomy for treating early gastric cancer (EGC). The subtype analysis revealed mantle cell lymphoma (MCL) of the blastic variant with a leukemic presentation, which was composed of mixed small and medium-sized cells. The immunohistochemical staining for cyclin-D1 was positive. The cytogenetic study revealed t(4;6). In Korea, the risk of developing a second primary cancer following gastric cancer was reported to be less than 3.4%, and NHL comprised less than 6.3% of this second primary cancer. Furthermore, MCL represents about 2% of all lymphomas in Korea. To the best of our knowledge, this is the first report of metachronous primary MCL with a leukemic presentation following curative resection of EGC. (Korean J Hematol 2008;43:247-252.)

참고자료

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