한국인 건강 검진자의 나이와 체질량지수에 따른 위식도역류질환의 유병률 (The Prevalence of Gastroesophageal Reflux Disease Associated with Age and Body Mass Index in Healthy Koreans)

서지정보

· 발행기관 : 대한노인병학회
· 수록지 정보 : Annals of geriatric medicine and research / 12권 / 4호 / 201 ~ 206페이지
· 저자명 : 강효성, 남승우, 이성은, 권혁춘, 박상민, 양성욱, 윤주화, 유지원, 이근숙, 나수지

초록

Background: The prevalence of obesity is increasing year after year in K orean; and gastroesophageal reflux
disease (GERD) is increasing in this population as well. The aim of this study is to assess the association between age,
body m ass index (B M I) and G E R D in healthy K orean adults.
M ethods: A nalysis w as done on 1,016 subjects w ho had not had m alignancy, uncontrolled m etabolic disease,
enteric surgery and organic esophageal disease. They completed a questionnaire that included past history and reflux
sym ptom s. Endoscopy was perform ed by two gastroenterologists who were not given any patient inform ation. Existence
of G E R D w as determ ined by the esophageal syndrom e criteria of the M ontreal guidelines. S ubjects w ere
categorized by B M I, initially as: underw eight, norm al (18.5≤B M I<25), overw eight (25≤B M I<30) and obese by the
W HO criteria, and then as: underweight, norm al (18.5≤BM I<23), overweight (23≤BM I<25) and obese by the Asian-
P acific criteria.
Results: The overall [is this correct] prevalence of GERD in our subjects was 15.5% . Age and sex were not correlated
factors for G E R D . B y the W H O and the A sian-P acific criteria , G E R D w as present in underw eight (10.0% ,
12.1%), normal (13.9%, 14.4%), overweight (18.6%, 13.0%) and obese groups (21.0%, 18.8%). No meaningful association
was seen between BM I and G ERD in either of the classified groups. Erosive GERD was seen in 83 subjects
(8.2% ) on endoscopy. The obese (B M I≥25) group (12.1% ) show ed a m eaningful increm ent in the prevalence of
erosive G E R D com pared to the non-obese (B M I<25) group (6.2% ) (p value 0.002).
C onclusion: The prevalence of G E R D in healthy K orean adult subjects w as not closely associated w ith obesity
and age [according to B M I]; how ever, erosive G E R D w as found to have a strong association w ith obesity.

영어초록

Background: The prevalence of obesity is increasing year after year in K orean; and gastroesophageal reflux
disease (GERD) is increasing in this population as well. The aim of this study is to assess the association between age,
body m ass index (B M I) and G E R D in healthy K orean adults.
M ethods: A nalysis w as done on 1,016 subjects w ho had not had m alignancy, uncontrolled m etabolic disease,
enteric surgery and organic esophageal disease. They completed a questionnaire that included past history and reflux
sym ptom s. Endoscopy was perform ed by two gastroenterologists who were not given any patient inform ation. Existence
of G E R D w as determ ined by the esophageal syndrom e criteria of the M ontreal guidelines. S ubjects w ere
categorized by B M I, initially as: underw eight, norm al (18.5≤B M I<25), overw eight (25≤B M I<30) and obese by the
W HO criteria, and then as: underweight, norm al (18.5≤BM I<23), overweight (23≤BM I<25) and obese by the Asian-
P acific criteria.
Results: The overall [is this correct] prevalence of GERD in our subjects was 15.5% . Age and sex were not correlated
factors for G E R D . B y the W H O and the A sian-P acific criteria , G E R D w as present in underw eight (10.0% ,
12.1%), normal (13.9%, 14.4%), overweight (18.6%, 13.0%) and obese groups (21.0%, 18.8%). No meaningful association
was seen between BM I and G ERD in either of the classified groups. Erosive GERD was seen in 83 subjects
(8.2% ) on endoscopy. The obese (B M I≥25) group (12.1% ) show ed a m eaningful increm ent in the prevalence of
erosive G E R D com pared to the non-obese (B M I<25) group (6.2% ) (p value 0.002).
C onclusion: The prevalence of G E R D in healthy K orean adult subjects w as not closely associated w ith obesity
and age [according to B M I]; how ever, erosive G E R D w as found to have a strong association w ith obesity.

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