하부요로증상이 있는 여성에서 압력요류검사 지표들과 요도내압의 연관성 (The Relationship of Pressure-Flow Parameters and Urethral Pressure in Female Patients with Lower Urinary Tract Symptoms)

서지정보

· 발행기관 : 대한비뇨의학회
· 수록지 정보 : Investigative and Clinical Urology / 50권 / 6호 / 567 ~ 572페이지
· 저자명 : 우종현, 홍성주, 이종복

초록

Purpose: This study aimed to evaluate the relationship between pressure- flow parameters and urethral pressure in women with lower urinary tract symptoms (LUTS).
Materials and Methods: Urodynamic traces of women with stress urinary incontinence (SUI), mixed urinary incontinence (MUI), and detrusor overactivity (DO) were retrospectively studied. The urodynamic parameters such as detrusor opening pressure (DOP), detrusor pressure at maximum flow rate (PdetQmax), maximum flow rate (Qmax), detrusor closing pressure (DCP), and maximal urethral closing pressure (MUCP) were measured and compared. The relationship between pressure-flow parameters and MUCP were evaluated as well as the differences between each urodynamic group.
Results: One hundred fifty-one women were investigated between June 2004 and May 2008. One hundred twenty-one (80%) women had good- quality urodynamic studies and were included in the present study. The mean age was 56 years (range, 32-77). Women with DO had higher DOP, PdetQmax, and MUCP than did women with SUI (p＜0.05). Qmax was significantly greater in women with SUI than in women who had DO (p＜0.05). Women with MUI had DOP, PdetQmax, and Qmax that were intermediate between women with SUI and those with DO. There was a significant positive correlation between DOP, PdetQmax, DCP, and MUCP measurements and a significant negative correlation between Qmax and MUCP measurements (p＜0.01).
Conclusions: Pressure-flow parameters are reliable surrogates of urethral pressure. Therefore, an accurate evaluation of the pressure-flow parameters might give important information in the assessment of urethral and detrusor function in women with LUTS. Further study is needed to confirm our results.

영어초록

Purpose: This study aimed to evaluate the relationship between pressure- flow parameters and urethral pressure in women with lower urinary tract symptoms (LUTS).
Materials and Methods: Urodynamic traces of women with stress urinary incontinence (SUI), mixed urinary incontinence (MUI), and detrusor overactivity (DO) were retrospectively studied. The urodynamic parameters such as detrusor opening pressure (DOP), detrusor pressure at maximum flow rate (PdetQmax), maximum flow rate (Qmax), detrusor closing pressure (DCP), and maximal urethral closing pressure (MUCP) were measured and compared. The relationship between pressure-flow parameters and MUCP were evaluated as well as the differences between each urodynamic group.
Results: One hundred fifty-one women were investigated between June 2004 and May 2008. One hundred twenty-one (80%) women had good- quality urodynamic studies and were included in the present study. The mean age was 56 years (range, 32-77). Women with DO had higher DOP, PdetQmax, and MUCP than did women with SUI (p＜0.05). Qmax was significantly greater in women with SUI than in women who had DO (p＜0.05). Women with MUI had DOP, PdetQmax, and Qmax that were intermediate between women with SUI and those with DO. There was a significant positive correlation between DOP, PdetQmax, DCP, and MUCP measurements and a significant negative correlation between Qmax and MUCP measurements (p＜0.01).
Conclusions: Pressure-flow parameters are reliable surrogates of urethral pressure. Therefore, an accurate evaluation of the pressure-flow parameters might give important information in the assessment of urethral and detrusor function in women with LUTS. Further study is needed to confirm our results.

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