Clinical Usefulness of Regional Tissue Oxygen Saturation Monitoring Using Near-Infrared Spectroscopy in Neonates

서지정보

· 발행기관 : 대한주산의학회
· 수록지 정보 : Perinatology / 33권 / 1호 / 21 ~ 26페이지
· 저자명 : 이성희, 윤소진, 임주희, 한정호, 신정은, 이순민, 은호선, 박민수

초록

Objective: Recently, near-infrared spectroscopy (NIRS) has been introduced in the neonatal intensive care unit (NICU) to monitor the altered hemodynamic status causing cerebral hypoxemia or affecting mesenteric and/or renal oxygenation. This study aimed to reassess the clinical usefulness of NIRS and the correlation between regional O2 saturation (rSO2) and various physiological parameters in neonates.
Methods: Thirty-nine newborns, admitted in NICU from June 2019 to June 2020 and continuously monitored with NIRS (cerebral and renal) during the first 72 hours, were included.
Results: Among 39 newborns with a median gestational age of 33.9 weeks, and a median birth weight of 2,180 g, the median of the cerebral and renal rSO2 were 84% (30%–95%) and 95% (45%–95%), respectively. Cerebral rSO2 tended to increase over time since the time of delivery, while renal rSO2 tended to decline, especially in preterm infants. Average of renal rSO2 during 72 hours showed a statistically significant difference between term and preterm infants (P<0.05). Cerebral rSO2 showed significant correlation with hemoglobin (r=0.35, P<0.05) and hematocrit (r=0.37, P<0.05). Renal rSO2 showed significant correlation with capillary blood gas analysis such as pH (r=0.36, P<0.05), pCO2 (r=-0.19, P<0.05), pO2 (r=0.23, P<0.05), base excess (r=0.19, P<0.05), hemoglobin (r=0.33, P<0.05), hematocrit (r=0.32, P<0.05) as well as renal function indicator such as blood urea nitrogen (r=-0.50, P<0.05) and creatinine (r=-0.59, P<0.05).
Conclusion: We re-evaluated the clinical usefulness of NIRS in neonates by identifying trends and correlations of rSO2 with clinical parameters. It is necessary to confirm its effectiveness through further study.

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