뇌 자기공명촬영을 이용한 중뇌부 동안신경속 배열의 3차원 모델 (3-D Model of The Oculomotor Fascicular Arrangement Within The Midbrain Using Brain MRI)

서지정보

· 발행기관 : 대한평형의학회
· 수록지 정보 : Research in Vestibular Science / 7권 / 1호 / 22 ~ 32페이지
· 저자명 : 박정호, 정두신, 박선아, 이태경, 성기범

초록

Background and Purpose: The oculomotor nerve fascicles arise along its entire length and sweep ventrally to
exit the midbrain at the medial edge of the crus cerebri. A rostro-caudal topography among the fascicular fibers
is relatively well established. There are, however, some controversies whether medio-lateral topography also exists.
Methods: We retrospectively reviewed the clinical records and MRI of the 8 patients showing isolated
oculomotor nerve palsy due to midbrain infarction. Brain MRI was performed using a 1.5-T magnet with 2mm
thickness and 0.1 mm slice interval. The anterior-posterior axis(X) was defined as the midline crossing the center
of the cerebral aqueduct and the medio-lateral axis(Y) as the line crossing the same point. For rostro-caudal
measurement, the intercommissural line was used as base line of the Z axis. The location of the lesions was
defined by measuring actual distance of the margins of the lesions in millimeter from each axis; anterior, right,
and caudal direction was defined as positive values in X, Y and Z coordinates, respectively.
Results: The mean values and range of the X, Y and Z are as follows: X=7.56±4.34, 1≤X≤15; Y=3.43±1.37,
0≤Y≤6; Z=6.51±3.91, 0≤Z≤12.5.
Conclusions: The distribution of all the MRI lesions was 0≤|Y|≤6 (mm), 0≤|Z|≤12.5 (mm) in mediolateral
and rostrocaudal direction respectively, which is almost the same as the previously reported divergent range of the
oculomotor fascicles in midbrain tegmentum. We suggest that our method of three dimensional measurements of
the MRI lesion in midbrain tegmentum could be a useful tool for the study of oculomotor fascicular arrangement.

영어초록

Background and Purpose: The oculomotor nerve fascicles arise along its entire length and sweep ventrally to
exit the midbrain at the medial edge of the crus cerebri. A rostro-caudal topography among the fascicular fibers
is relatively well established. There are, however, some controversies whether medio-lateral topography also exists.
Methods: We retrospectively reviewed the clinical records and MRI of the 8 patients showing isolated
oculomotor nerve palsy due to midbrain infarction. Brain MRI was performed using a 1.5-T magnet with 2mm
thickness and 0.1 mm slice interval. The anterior-posterior axis(X) was defined as the midline crossing the center
of the cerebral aqueduct and the medio-lateral axis(Y) as the line crossing the same point. For rostro-caudal
measurement, the intercommissural line was used as base line of the Z axis. The location of the lesions was
defined by measuring actual distance of the margins of the lesions in millimeter from each axis; anterior, right,
and caudal direction was defined as positive values in X, Y and Z coordinates, respectively.
Results: The mean values and range of the X, Y and Z are as follows: X=7.56±4.34, 1≤X≤15; Y=3.43±1.37,
0≤Y≤6; Z=6.51±3.91, 0≤Z≤12.5.
Conclusions: The distribution of all the MRI lesions was 0≤|Y|≤6 (mm), 0≤|Z|≤12.5 (mm) in mediolateral
and rostrocaudal direction respectively, which is almost the same as the previously reported divergent range of the
oculomotor fascicles in midbrain tegmentum. We suggest that our method of three dimensional measurements of
the MRI lesion in midbrain tegmentum could be a useful tool for the study of oculomotor fascicular arrangement.

참고자료

· 없음