Detection of Hepatic Lesion: Comparison of Free- Breathing and Respiratory-Triggered Diffusion- Weighted MR imaging on 1.5-T MR system

서지정보

· 발행기관 : 대한자기공명의과학회
· 수록지 정보 : Investigative Magnetic Resonance Imaging / 15권 / 1호 / 22 ~ 31페이지
· 저자명 : 박혜영, 조현제, 김은미, 허감, 김용훈, 이병훈

초록

Purpose : To compare free-breathing and respiratory-triggered diffusion-weighted imaging on 1.5-T MR system in the detection of hepatic lesions.
Materials and Methods : This single-institution study was approved by our institutional review board. Forty-seven patients (mean 57.9 year; M:F = 25:22) underwent hepatic MR imaging on 1.5-T MR system using both free-breathing and respiratory-triggered diffusion-weighted imaging (DWI) at a single examination. Two radiologists retrospectively reviewed respiratory-triggered and free-breathing sets (B50, B400,B800 diffusion weighted images and ADC map) in random order with a time interval of 2 weeks. Liver SNR and lesion-to-liver CNR of DWI were calculated measuring ROI.
Results : Total of 62 lesions (53 benign, 9 malignant) that included 32 cysts, 13hemangiomas, 7 hepatocellular carcinomas (HCCs), 5 eosinophilic infiltration, 2metastases, 1 eosinophilic abscess, focal nodular hyperplasia, and pseudolipoma of Glisson’s capsule were reviewed by two reviewers. Though not reaching statistical significance, the overall lesion sensitivities were increased in respiratory-triggered DWI [reviewer1: reviewer2, 47/62(75.81%):45/62(72.58%)] than free-breathing DWI [44/62(70.97%):41/62(66.13%)]. Especially for smaller than 1 cm hepatic lesions,sensitivity of respiratory-triggered DWI [24/30(80%):21/30(70%)] was superior to freebreathing DWI [17/30(56.7%):15/30(50%)]. The diagnostic accuracy measuring the area under the ROC curve (Az value) of free-breathing and respiratory-triggered DWI was not statistically different. Liver SNR and lesion-to-liver CNR of respiratorytriggered DWI (87.6±41.4, 41.2±62.5) were higher than free-breathing DWI (38.8±13.6, 24.8±36.8) (p value <0.001, respectively).
Conclusion : Respiratory-triggered diffusion-weighted MR imaging seemed to be better than free-breathing diffusion-weighted MR imaging on 1.5-T MR system for the detection of smaller than 1 cm lesions by providing high SNR and CNR.

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