서울대학교 유기무기실험 유기 part lab report 1 selective allylation of benzyl alcohol

목차

1. INTRODUCTION
2. RESULTS
3. CONCLUSIONS AND DISCUSSION

본문내용

ABSTRACT: In this experiment, one of the hydroxyl groups of 1,4-benzenedimethanol was selectively protected using TBSCl. Subsequently, PDC was employed to oxidize the unprotected alcohol to an aldehyde. The final product was ob-tained by reacting the aldehyde with a Grignard reagent of unknown structure. The structure of the Grignard reagent was identified by interpreting the ¹H NMR, ¹³C NMR, and COSY NMR spectra of the final product.

참고자료

· Bajwa, J. S.; Prasad, K.; Repic, O. 2-(2’,2’-Dimethylpropoxy)-2,3-Dihydro-1H-Indene. Organic Syntheses. 2006, 83 (155).
· Piancatelli, G.; Luzzio, F. A. “Pyridinium Chlorochromate” e-EROS Encyclopedia of Reagents for Organic Synthesis; John Wiley & Sons, 2007.
· Peltzer, R. M.; Gauss, J.; Eisenstein, O.; Cascella, M. The Grignard Reaction – Unraveling a Chemical Puzzle. Journal of the American Chemical Society. 2020, 142 (6).
· Theodora W. Greene; Peter G. M. Wuts. Protectiong Groups in Organic Synthesis; J. Wiley, 1999.
· Goebel, M. T.; Marve, C. S. The Oxidation of Grignard Reagents. Journal of the American Chemical Society. 1933, 55 (4), 1693-1696.
· Dolphe W. Sur une nouvelle classe de radicaux organiques. An-nales de chimie et de physique. 1855, 44, 275-312.