[유전공학] IGF2R 유전자

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목차

1 서문
2 Gene information
3 Multiple gene function
① Intellectual faculty
② Indirect effect on Alzheimer's disease
③ Tumor suppressor of Hepatocellular carcinoma
④ No influence on birth size
4 맺음말
5 참고자료
6 사진 그래프 표 자료 등등

본문내용

1. Gene information

① Name: IGF2R, insulin-like growth factor 2 receptor [Homo sapiens]
- Gene aliases: HGNC:5467, CD222, CIMPR, M6P-R, MPRI
② Transcripts and products: RefSeq (material 1, figure 1)
③ Location: chromosome 6, 6q26
- For mapping the gene IGF2R to 6q26, cloned cDNA is used as a probe to hybrid DNA. By using the fluorescence in situ hybridization we can know the location 6q26. In mouse, IGF2R is located on chromosome 17, and CD-MPR is mapped to chromosome 12.
④ Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; Hominidae; Homo
⑤ Gene ontology of function
- Insulin-like growth factor receptor activity (material 2), receptor activity (material 3), transporter activity (material 4)
⑥ Protein: Insulin-like growth factor 2 receptor
cation-independent mannose-6 phosphate receptor
⑦ Homologene: 676. Gene conserved in Coelomata (table 1)

참고 자료

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