채취시기별 보검선인장 줄기의 항산화, 항당뇨 및 항알츠하이머 활성평가

서지정보

ㆍ발행기관 : 한국식품영양학회 ㆍ수록지정보 : 한국식품영양학회지 / 30권 / 6호
ㆍ저자명 : 정윤숙, 황병순, 조수묵, 황경아, 황인국

목차

서 론
재료 및 방법
1. 재료
2. 추출물 조제
3. 총 폴리페놀 및 총 플라보노이드 함량
4. 항산화 활성 평가
5. 항당뇨 활성 평가
6. 항알츠하이머 활성 평가
결과 및 고찰
1. 총 폴리페놀 및 총 플라보노이드 함량
2. 항산화 활성 평가
3. 항당뇨 활성 평가
4. 항알츠하이머 활성 평가
요약 및 결론
감사의 글
References

영어 초록

In this study, we assessed antioxidant, anti-diabetic, and anti-Alzheimer activities of Opuntia ficus-indica var. saboten (OFI) at harvest time. OFIs were cultivated December 2015~November 2016 in Jeju island. The 70% ethanol extracts of OFI were used to investigate total polyphenol and flavonoid contents, antioxidant(DPPH and ABTS radical scavenging assay), anti-diabetic(yeast α-glucosidase and rat α-glucosidase inhibition assay), and anti-Alzheimer(Acetylcholinesterase and butyrylcholinesterase inhibition assay) activities. Total polyphenol and flavonoid contents of OFIs were 17.40~23.11 μg garlic acid/mg Ex and 2.17~6.22 ug (+)-catechine/mg Ex, respectively. DPPH and ABTS radical scavenging activity of OFIs were 131.98~184.90 mg ascorbic acid(AA) eq/100 g and 63.60~101.83 mg AA eq/100 g, respectively. In the anti-diabetic and anti-Alzheimer activities, 70% ethanol extracts of OFI exhibited moderate inhibition activity, compared to control (acarbose and beberine). Total polyphenol and flavonoid contents, antioxidant, anti-diabetic, and anti-Alzheimer activities were no significant differences by season, respectively. Therefore, information on comparative biological evaluations of OFI may be a beneficial in exploring functional food and drug development.

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