ACUTE MYELOGENOUS LEUKEMIA
- 최초 등록일
- 2000.10.08
- 최종 저작일
- 2000.10
- 8페이지/ 한컴오피스
- 가격 1,000원
목차
Introduction
Etiology and Epidemiology
Natural History
Teatment of Newly Diagnosed AML
Treatment of Relapsed and Refractory AML
본문내용
Introduction
* The proliferation of malignant myeloblasts and other immature myelocytic cell
* leukemic cell 이 BM infiltration hematopoiesis impairment
anemia, granulocytopenia,thrombocytopenia
* Untreated rapidly fatal
* Mean survival- less than 2 month
* Recent therapy;
① Intensive chemotherapy
② Autologous or allogenic bone marrow transplantation
Etiology and Epidemiology
* Incidence
5/10,000 in U.S.A.
no seasonal variation
* median age of onset; 50 yrs
* Etiology
① Hereditary disease; Down, Bloom, Klinefelter and Wiskott-Aldrich syndrome
② Ionizing radiation
③ Benzene, Toluene
④ Chloramphenicol
⑤ Several acquired disease;
myeloproliferative disorders, multiple myeloma, Hodgkin's disease and
non-Hodgkin's disease
⑥ Alkylating agent
Natural History
참고 자료
없음