Effects of dietary acetaminophen, vitamin C and thioctic acid supplements on stress responses in mice vaccinated with foot-and-mouth disease vaccine
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- 최초 등록일
- 2023.04.03
- 최종 저작일
- 2022.09
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서지정보
ㆍ발행기관 : 한국예방수의학회(구 한국수의공중보건학회)
ㆍ수록지정보 : 예방수의학회지 / 46권 / 3호
ㆍ저자명 : Jin-Kyoung Kim, Song-Ee Son, Won-Seok Chae, Suk Kim, Hu-Jang Lee
목차
Abstract
감사의 글
REFERENCES
영어 초록
This study evaluated the effect of a combination of acetaminophen (AAP), vitamin C (VC) and thioctic acid (TA) on reducing serum cortisol concentrations in mice with foot-and-mouth disease (FMD) vaccination. For 5 days from 3 days before FMD vaccination to 2 days after vaccination, mice were orally administered with AAP 600 mg/kg feed (n=25, AAPT), combination of AAP 600 mg and VC 200 mg per kg feed (n=25, AVCT) and combination of AAP 600 mg, VC 200 mg and TA 20 mg per kg feed (n=25, AVTT), respectively. From day 1 to day 7 after FMD vaccination, the cortisol concentration of all groups treated with the drug was significantly decreased compared to that of the positive control group with FMD vaccination (p<0.05). In conclusion, the combined treatment of AAP, VC and TA was the most effective in relieving stress from FMD vaccination compared to the single treatment.
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