AIDS 에이즈 와 HIV 인간 면역결핍 바이러스

소개글

본 자료는 HIV(인간 면역 결핍 바이러스, human immunodeficiency virus)와 후천성 면역 결핍증(AIDS) Acquired Immune Deficiency Syndrome 에 대한 개념과 치료에 관한 요약입니다.

목차

(1) 원인
(2) 감염경로
(3) HIV-1 virion
(4) Contol
(5) HIV life cycle
(6) 약물치료

본문내용

■ 약물치료제의 종류
1) Attachment/Entry/fusion inhibitors : interfere with binding, fusion and entry of virus to the host cell
– CCR5 receptor antagonists(entry 저해제) : T-cell 표면의 CCR5 receptor에 결합하여 바이러스 entry 저해
– gp41 blocker(fusion 저해제) : 바이러스의 capsid가 들어올 pore 형성을 억제하여 fusion 저해
2) Nucleoside/nucleotide reverse transcriptase inhibitors(NRTI)
: inhibit reverse transcription by being incorporated into the newly synthesized viral DNA strand as faulty nucleotides
3) Non-Nucleoside reverse transcriptase inhibitors (NNRTI)
: inhibit reverse transcriptase by binding to an allosteric site of the enzyme
4) Integrase inhibitors
: inhibit integrase, which is responsible for integration of viral DNA into the DNA of the infected cell
5) Protease inhibitors (PIs)
: target viral assembly by inhibiting the activity of protease, an enzyme used by HIV to cleave nascent proteins for the final assembly of new virions

참고 자료

킴스온라인
약물치료학, 신일북스
Micromedex