ASCB mini symposium 2

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Mini symposium : Host-pathogen interactions
Dissecting Host-pathogen interactious in real time.
Many Gram-negative pathogenic bacteria employ a complex protein secretion system termed type III secretion system (TTSS) to transport bacterial effector proteins across three membrane barriers into eukaryotic host cytoplasm. The effector proteins delivered by TTSS are capable of modulating and interfering with the host cellular processes, which cause diseases in animals and plants such as plague, typhoid fever, bacterial dysentery.  The TTSS is composed of more than 20 structural proteins, effector proteins, and chaperones. 
Salmonella infection cycle
Epithelial cell에 infection 했다가 macrophage에 infection.
Effecter protein : SPI-1 -> SPI-2

Effecter에 3XTC tag을 달았다.
3XFIASH-EDT2

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