구루병 등 대사성 골질환 정리

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구루병 등에 관한 전반적인 내분비성, 대사성 장애에 관한 정리입니다.

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본문내용

Vitamin D metabolism
Ca, P and Vit. D
Rickets Definition
An osteomalacic syndrome
Failure of mineralization of
chondroid and osteoid
Lack of ionized calcium and/or phosphate
Less mineralized bone per unit volume of bone
Bowing deformities
Stress fractures with resultant deformities
Biochemical consequencesof vitamin D deficiency rickets
Vitamin D deficiency
Reduced Ca absorption
Depressed extracellular Ca
Secondary hyperparathyroidism
Depressed extracellular P
Defective minerlization of the bone in formation
Increased bone resorption
Demineralization of the existing bone
Severe osteomalacia:
Marked increased in osteoid
bordering trabecular and endosteal bone
20% in normal bone)

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