중요 항생제의 분류와 식품안전분야에서 활용
(주)코리아스칼라
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- 2023.09.25
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- 2023.08
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서지정보
ㆍ발행기관 : 한국식품위생안전성학회
ㆍ수록지정보 : 한국식품위생안전성학회지 / 38권 / 4호
ㆍ저자명 : 곽효선, 함준혁, 김이슬, 채은화, 정상희, 김해영
목차
ABSTRACT
항생제를 중요도에 따라 3개 그룹으로 분류
‘최우선 중요 항생제’ 선정
WHO AGISAR 전문가 그룹에서 지속적인 CIA 검토
CIA 목록의 의의 및 활용
식품안전 분야에서의 중요 항생제 목록 활용
국가별 특성에 따른 중요 항생제 목록 재분류 필요성
Conclusion
Acknowledgement
국문요약
Conflict of interests
ORCID
References
영어 초록
Antimicrobials in human medicine are classified by The World Health Organization (WHO) into three groups: critically important antimicrobials (CIA), highly important antimicrobials (HIA), and important antimicrobials (IA). CIA are antibiotic classes that satisfy two main criteria: that they are the sole or the only available limited therapeutic option to effectively treat severe bacterial infections in humans (Criterion 1), and infections where bacteria are transmitted to humans from non-human sources or have the potential to acquire resistance genes from non-human sources (Criterion 2). WHO emphasizes the need for cautious and responsible use of the CIA to mitigate risk and safeguard human health. Specific antimicrobials within the CIA with a high priority for management are reclassified as “highest priority critically important antimicrobials (HP-CIA)” and include the 3rd generation of cephalosporins and the next generation of macrolides, quinolones, glycopeptides, and polymyxins. The CIA list is the scientific basis for risk assessment and risk management policies that warrant using antimicrobials to reduce antimicrobial resistance in several countries. In addition, the CIA list ensures food safety in the food industry, including for the popular food chain companies McDonald's and KFC. The continuous update of the CIA list reflects the advancement in research and emerging future challenges. Thus, active and deliberate evaluation of antimicrobial resistance and the construction of a list that reflects the specific circumstances of a country are essential to safeguarding food security.
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