HPLC를 이용한 건강기능식품 중 코엔자임 Q10 성분 분석
(주)코리아스칼라
- 최초 등록일
- 2023.04.05
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- 2011.03
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서지정보
ㆍ발행기관 : 한국식품위생안전성학회
ㆍ수록지정보 : 한국식품위생안전성학회지 / 26권 / 1호
ㆍ저자명 : 노기미, 임동길, 김미경, 박경식, 윤태형, 홍진, 박선영, 정자영
영어 초록
A method based on high-performance liquid chromatography (HPLC) with ultraviolet detection has been developed to quantify coenzyme Q10 (CoQ10) in raw materials and dietary supplements. Single-laboratory validation has been performed on the method to determine linearity, selectivity, accuracy, limits of quantification (LOQ) and repeatability for CoQ10. An excellent linearity (r = 0.999) was observed for CoQ10 in the concentration range 15.625~500 μg/mL in dietary supplement. Observed recovery of CoQ10 was found to be between 98.33 and 99.38%. LOQ was found to be 250 μg/mL Repeatability precision for CoQ10 was between 0.15 and 0.21% relative standard deviation (RSD). Further, limited studies showed that some adulterants and degraded material could be satisfactorily separated from CoQ10 and identified.
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