IGFBP2 유전자 C1032T SNP가 닭의 산란 및 육량 형질에 미치는 영향
(주)코리아스칼라
- 최초 등록일
- 2023.04.05
- 최종 저작일
- 2015.06
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서지정보
ㆍ발행기관 : 강원대학교 동물자원공동연구소
ㆍ수록지정보 : 동물자원연구 / 26권 / 1호
ㆍ저자명 : 최소영, 원종영, 김종대, 홍영호, 정동기, 이성진
영어 초록
The insulin-like growth factor binding proteins (IGFBPs) is involved in the regulating effects and the biological activities of the insulin-like growth factors (IGFs). Recently, It has been reported that the IGFBP2 gene polymorphism was associated growth and skeletal development in chicken. This study was designed to investigate the association of the C1032T SNP of IGFBP2 gene with growth and egg production traits in Korean native chicken (KNC) population as well as other chicken breeds. A total of 225 chickens from the three breeds (Rhode Island Red, Cornish, Leghorn) and 245 chickens from the six strains of Korean native chickens including Black, Gray, Ogol, Red, White, and Yellow, were genotyped by PCR-RFLP (polymerase chain reaction-restricted fragment length polymorphism) and analyzed the association between their genotypes and economic traits by SAS program. The results showed that the SNP (single nucleotide polymorphism) was significantly associated with multiple traits, including body weight of 150 days (p<0.001 and p<0.05) in the Rhode Island Red and the KNC (White) and egg production number (p<0.05) in the KNC (Black) breed. These results suggest that IGFBP2 C1032T SNP could be used as a DNA marker for the improvement of economic traits in Korean native chicken breeding.
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