Characterization of Quantitative Trait Loci (QTL) for Growth using Genome Scanning in Korean Native Pig
(주)코리아스칼라
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- 2016.04.01
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- 2004.06
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서지정보
ㆍ발행기관 : 한국동물번식학회
ㆍ수록지정보 : Reproductive & developmental biology / 28권 / 2호
ㆍ저자명 : Lee, H. K., I. S. Choi, B. H. Choi, T. H. Kim, I. J. Jung
목차
INTRODUCTION MATERIAL & METHODS Experimantal population and performance traits DNA, isolation, marker selection and genotyping Statistical Analysis RESULT AND DISCUSSION REFERENCES
영어 초록
Molecular genetic markers were genotyped used to detect chromosomal regions which contain economically important traits such as growth traits in pigs. Three generation resource population was constructed from a cross between the Korean native boars and Landrace sows. A total of 193 F2 animals from intercross of F1 were produced. Phenotypic data on 7 traits, birth weight, body weight at 3, 5, 12, 30 weeks of age, live empty weight were collected for F2 animals. Animals including grandparents (F0), parents (F1), offspring (F2) were genotyped for 194 microsatellite markers covering from chromosome 1 to 18. Quantitative trait locus analyses were performed using interval mapping by regression under line-cross model. To characterize presence of imprinting, genetic full model in which dominance, additive and imprinting effect were included was fitted in this analysis. Significance thresholds were determined by permutation test. Using imprinting full model, four QTL with expression of imprinted effect were detected at 5% chromosome-wide significance level for growth traits on chromosome 1, 5, 7, 13, 14, and 16.
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