[혈액종양 의학]난소암 ovarian cancer

소개글

a+ 받은 정말 내용알찬 review 입니다

표도 많고 해리슨 그림도 있습니다

목차

I. Modified WHO comprehensive classification of ovarian tumors

II. Ovarain cancer (전반적인 고찰)

III. Epithelial Ovarian Cancer (이하 EOC)

이게 큰 분류구요

본문내용

Below are several treatment options for individuals with ovarian cancer.

Option 1: cisplatin (Platinol) and paclitaxel (Taxol)
route: IV
duration of time: Given every 21 days for 4-6 treatments (6 months)
side effects: cisplatin - neurotoxicity , nephrotoxicity, ototoxicity
paclitaxel - neurotoxicity

Option 2: carboplatin (Paraplatin) and paclitaxel (Taxol)
Carboplatin 역시 platinum 화합물이지만, 그것의 toxicity profile은 cisplatin의 것과는 다르다. Carboplatin은 신경계, 신장에 부작용이 없거나 거의 없다. 더구나 더 쉽게 투여할수 있으며 그래서 IV hydration을 요하지 않는다.
route: IV
duration of time: Given every 21-28 days for 4-6 treatments.
side effects: Carboplatin - thrombocytopenia, nausea, vomiting, peripheral neurotoxicity , arthralgia

Option 3: melphalan
Melphalan은 alkylating agent 또는 "mustard"로 stage 3나 stage4의 bulky ovarian cancer에 일부 효과가 있다.
route: PO
duration of time: Given daily for 5 days as a single course; repeated every 4 to 5 weeks
side effects: BM suppression, irreversible BM failure, infrequent gastrointestinal symptom (nausea, vomiting, diarrhea, oral ulceration)

Option 4: Chemotherapy with cisplatin (Platinol), paclitaxel (Taxol), doxorubicin (Adriamycin); also called CAP
route: IV
duration of time: Given every 21 days for 4-6 treatments (6 months)
side effects: cisplatin - neurotoxicity, nephrotoxicity, ototoxicity;
paclitaxel - neurotoxicity

Second-Line Treatment Options
Below are "salvage" treatment options for individuals with resistant ovarian cancer.

참고 자료

해리슨 chemotherapy manual