아토피의 최신지견

목차

1.Introduction
2.Clinical manifestation
3.DDx.
4.Laboratory test
5.Biomarker
6.Human Beta-defensin-2 in AD
7.Vitamin D in AD
8.Serum GRP in AD
9.Triggering factor
10.Microbes
11.Sweating response

본문내용

Introduction

AD is a familial, chronic inflammatory skin disease that commonly presents during early infancy and childhood but can persisit or start in adulthood

Concordance rate
Monozygotic twin (77%)
Dizygotic twin (15%)

Prevalance
10~20% of children
1~3% of adults

Clinical manifestation

Develops before the age of 5 years
Develops in adulthood in 20%

“The atopic march”
AD -> allergic rhinitis, asthma

Acute AD
Pruritic erythematous papules associated with excoriation
Vesicles over erythematous skin with serous exudate

Chronic AD
Thickened plaques
Accentuated skin markings (Lichenification)
Fibrotic papules (Prurigo nudularis)

참고 자료

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