농장 맞춤형 자가배양시스템을 이용한 복합 생균제 적용 연구
(주)코리아스칼라
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- 2023.06.19
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- 2020.12
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서지정보
ㆍ발행기관 : 한국유산균학회
ㆍ수록지정보 : Current Topic in Lactic Acid Bacteria and Probiotics / 6권 / 2호
ㆍ저자명 : 이웅지, 윤보현, 이학교, 허재영, 김영훈, 오상남
목차
Abstract
서 론
재료 및 방법
사용 균주
내산성 및 내담즙성 평가
항균 활성
항생제 내성
Caenorhabditis elegans 부착 능력 평가
Multi-strain probiotics(MSP)의 농장 급여 및 사료 분석
농장 자가배양시스템을 위한 배지 조성
장내 미생물 분석
결 과
MSP의 probiotic 특성
MSP의 항균 활성과 항생제 저항성 평가
농장 자가배양시스템을 이용한 MSP의 급여
MSP급여로 인한 돼지 장내 microbial composition의 변화
고 찰
감사의 글
References
영어 초록
The status of probiotics is increasing worldwide and the range of application of probiotics is also being extended to the livestock industry. The use of probiotics in the swine industry aims to improve animal health and productivity by forming a healthy gut microbiota. Intensive pig breeding, a common breeding method in modern society, causes physiological stress in pigs, resulting in imbalance of the intestinal microbiota and dysfunction of the intestinal barrier. We conducted a scientific research on the properties of probiotics for multi-strain probiotics (MSP) and observed the economic benefits and efficiency of culturing MSP through a self-cultivation system in livestock. Initially, we observed alteration occurred by MSP application in the gut microbiota of pig. MSP were characterized to have resistance to digestive juices such as gastric acid and bile, followed by colonization in the target organ, the gastro-intestinal tract (GIT). In addition, MSP was also confirmed to have antibacterial ability against pathogenicity that most frequently infected in the swine industry and showed low resistance to antibiotics which means guaranteed stability when added to feed. The growth rate of probiotics in the optimized medium used in the self-cultivation system was suitable for efficiently and economically culturing and feeding pigs with high concentrations of probiotics, considering the ingredient price and the growth efficiency. We observed the significant alteration of gut microbiota of pig by application of MSP. Importantly, the MSP supplementation significantly increased the beneficial bacteria genus of Bifidobacterium that confer a health benefit to the host in pig GIT, whereas decreased the number of harmful bacteria including coliforms. In addition, MSP influenced on the uniformity of gut microbiota at both of sow and weaning pigs. Taken together, the application of MSP with high concentration of probiotics using self-cultivation system may critically improve the pig health by regulation intestinal microbiota.
참고 자료
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