용매별 정향 추출물의 항산화 및 신경세포 보호 효과
(주)코리아스칼라
- 최초 등록일
- 2023.04.05
- 최종 저작일
- 2017.12
- 6페이지/ 어도비 PDF
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서지정보
ㆍ발행기관 : 한국식생활문화학회
ㆍ수록지정보 : 韓國食生活文化學會誌 / 32권 / 6호
ㆍ저자명 : 오희경
목차
I. 서 론
II. 연구 내용 및 방법
1. 실험 재료 및 추출물의 제조
2. 총 polyphenol 함량
3. DPPH radical 소거활성
4. ABTS radical 소거활성
5. SOD 유사활성(Superoxide dismutase-like activity)
6. 신경세포 보호효과 측정
8. 통계처리
III. 결과 및 고찰
1. 총 polyphenol 함량
2. DPPH radical 소거활성
3. ABTS radical 소거활성 및 SOD 유사활성
4. 신경세포 보호효과
IV. 요약 및 결론
감사의 글
References
영어 초록
This study examined the antioxidant and neuronal cell protective effects of the water and methanol extracts of Eugenia caryophyllata Thunb. The total polyphenol content was significantly higher in the methanol extract than in the water extract. The DPPH radical scavenging activity in the water extract was similar to Vit. C at a concentration of 100~200 μg/mL. The ABTS radical scavenging activity in the water and methanol extract was similar to Vit. C at a concentration of 800~1,000 μg/mL. The superoxide dismutase (SOD)-like activity in the methanol extract was similar to Vit. C at a concentration of 800~1,000 μg/mL. The DPPH, ABTS radical scavenging and (SOD)-like activity increased with increasing extract concentration. In a cell viability using MTT, the water extract (50 and 100 ppm) and methanol extract (100 ppm) had a protective effect against H2O2-induced neurotoxicity.The result ssuggest that the extract of E. caryophyllata Thunb. has antioxidant activities and may be useful for treating neurodegenerative disorders.
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