IPF(Idiopathic pulmonary fibrosis 발표자료.

소개글

Idiopathic pulmonary fibrosis에 대해 정의, Pathogenesis, Management 등에 대해 설명한자료입니다.

목차

1. Introduction
2. Clinical presentation
3. Pathogenesis
4. Diagnosis
5. Management
6. Complications and mortality
7. Reference

본문내용

The family of ILD is characterized by cellular proliferation, interstitial inflammation, fibrosis, or a combination of such findings within the alveolar wall that is not due to infection or cancer.

IPF is of particular clinical interest because it is often misdiagnosed and managed inappropriately with immunosuppressive therapy, it is associated with a high mortality rate, and therapies that slow disease progression are now available.

Clinicians should consider interstitial lung disease in the differential diagnosis for adults presenting with unexplained exertional dyspnea, chronic dry cough, or Velcro-like crackles on examination.

Pulmonary function tests typically identify a reduced FVC, a reduced TLC, and a reduction in DLco.
In IPF, Bilateral reticulation is often predominant in the lower lung zones.

참고 자료

N Engl J Med 2018;378:1811-23.DOI: 10.1056/NEJMra1705751