Structure of AMP-PNP-bound BtuCD-F

목차

1. What is BtuCD-F?
2. Assembly of the BtuCD complex
3. Overall structure
4. Structure of the BtuC subunit.
5. Structure of the BtuD and interface of the ABC cassettes
6. Structure of the BtuF subunit.
7. Connect region between BtuC and BtuD
8. Interface between BtuF and BtuC

본문내용

What is BtuCD-F?
The Escherichia coli BtuCD-F protein complex, An ABC transporter mediating vitamin B12 uptake. Catalytic activity of BtuCD-F is ATP + H2O + vitamin B12(Out) = ADP + phosphate + vitamin B12(In). BtuC is involved in the translocation of the substrate across the membrane. BtuD is responsible for energy coupling to the transport system. BtuF is binds vitamin B12 and delivers it to the periplasmic surface of BtuC.

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