Cell surface Adhesion Receptors

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Cell surface Adhesion Receptors

목차

Cell surface Adhesion Recepter

Integrin

Cell surface Adhesion Recepter

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Cell surface Adhesion Recepter
Physiological processes in the host that are related to cell activation, proliferation, differentiation, or cellular motility
require cell-cell or cell-ECM contacts and are differentially mediated by adhesion receptors.

Integrin
Integrins are receptors that mediate attachment between a cell and the tissues
surrounding it, which may be other cells or the extracellular matrix (ECM).
They also play a role in cell signaling and thereby define cellular shape, mobility,
and regulate the cell cycle.
Typically,
receptors inform a cell of the molecules in its environment and the cell evokes a response. Not only do integrins perform this outside-in signalling,
but they also operate an inside-out mode.
Thus, they transduce information from the ECM to the cell
as well as reveal the status of the cell to the outside,
allowing rapid and flexible responses to changes in the environment.

Integrin
they transduce information from the ECM to the cell as well as reveal the status of the cell to the outside, allowing rapid and flexible responses to changes in the environment.

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