Xylooligosaccharide 의 랫트에 대한 급성 경구독성
(주)코리아스칼라
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- 2023.04.05
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- 1999.09
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서지정보
ㆍ발행기관 : 한국식품위생안전성학회
ㆍ수록지정보 : 한국식품위생안전성학회지 / 14권 / 3호
ㆍ저자명 : 이지완, 이창승, 윤세왕, 오화균, 양창근, 박윤재, 이운택, 류보경, 강부현
영어 초록
The acute toxicity of xylooligosaccharide(XO) was evaluated in SD rats. Groups of 15 male and 15 female rats were orally administered XO (0, 5000 or 10000 ㎎/㎏). The changes of body weight and clinical signs were investigated for 14 days after treatments. No death and toxic effects were observed for 14 days. Soft stool and diarrhea appeared right after treatment for over dose and non-digestive feature of XO but these clinical signs disappeared on the next day. No significant changes in body weight and abnormal gross findings were observed in relation to XO. According to the results, XO has no special toxic effects and LD50 values of XO are above 10000 ㎎/㎏ in male and female rats.
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