내분비계장애물질 대체소재의 안전성
(주)코리아스칼라
- 최초 등록일
- 2016.05.03
- 최종 저작일
- 2015.12
- 14페이지/ 어도비 PDF
- 가격 4,600원
* 본 문서는 배포용으로 복사 및 편집이 불가합니다.
서지정보
ㆍ발행기관 : 한국환경생물학회
ㆍ수록지정보 : 환경생물 / 33권 / 4호
ㆍ저자명 : 박찬진, 김웅, 계명찬
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영어 초록
Endocirne disruptors (EDs) can cause fertility decrease, developmental disorder, and even cancer in animals. Until 90’s, EDs were used in various synthetic products including paints, coatings, detergents, plastics, and plasticizers. Currently, in several countries, the production, trade and use of EDs or EDs-suspected chemicals have been regulated while activity to screen the alternatives for EDs including bisphenol-A, phthalate and nonylphenol is active. Although various toxicity test method was developed and applied for screening of alternatives, however, the safety of alternatives has been not fully demonstrated. Some alternatives have high structural similarity with existing EDs, raising the possible risk of endocrine disruption by alternatives. In an effort to develop the safe alternatives, we reviewed the effects of EDs such as bisphenol-A, phthalates, nonylphenol and their substituents. In addition, in-silico analysis for endocrine disrupting activities of some alternatives was presented.
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