Electro-responsive Transdermal Drug Release of MWCNT/PVA Nanocomposite Hydrogels
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서지정보
ㆍ발행기관 : 한국탄소학회
ㆍ수록지정보 : Carbon Letters / 11권 / 3호
ㆍ저자명 : Yeon-Yi Kim, Jumi Yun, Young-Seak Lee, Hyung-Il Kim
ㆍ저자명 : Yeon-Yi Kim, Jumi Yun, Young-Seak Lee, Hyung-Il Kim
목차
1. Introduction2. Experimental
3. Results and Discussion
4. Conclusions
References
한국어 초록
Multi-walled carbon nanotube (MWCNT)/poly(vinyl alcohol) (PVA) nanocomposite hydrogels were prepared by freezingthawingmethod for the electro-responsive transdermal drug delivery. MWCNTs were used as the functional ingredient to
improve both mechanical and electrical properties of MWCNT/PVA nanocomposite hydrogels. The morphology of
nanocomposites revealed the uniform distribution of MWCNTs and the good interfacial contact. The compression moduli of
hydrogel matrices increased greatly from 40 to 1500 kPa by forming MWCNT/PVA nanocomposites. The swelling ratio of
MWCNT/PVA nanocomposites decreased as the content of MWCNTs increased under no electric voltage applied. However,
the swelling ratio of MWCNT/PVA nanocomposites increased as the content of MWCNTs increased under electric voltage
applied and the applied electric voltage increased. The drug was released in the electro-responsive manner through the skin
due to the electro-sensitive swelling characteristics of MWCNT/PVA nanocomposite hydrogels.
영어 초록
Multi-walled carbon nanotube (MWCNT)/poly(vinyl alcohol) (PVA) nanocomposite hydrogels were prepared by freezingthawingmethod for the electro-responsive transdermal drug delivery. MWCNTs were used as the functional ingredient toimprove both mechanical and electrical properties of MWCNT/PVA nanocomposite hydrogels. The morphology ofnanocomposites revealed the uniform distribution of MWCNTs and the good interfacial contact. The compression moduli ofhydrogel matrices increased greatly from 40 to 1500 kPa by forming MWCNT/PVA nanocomposites. The swelling ratio ofMWCNT/PVA nanocomposites decreased as the content of MWCNTs increased under no electric voltage applied. However,the swelling ratio of MWCNT/PVA nanocomposites increased as the content of MWCNTs increased under electric voltageapplied and the applied electric voltage increased. The drug was released in the electro-responsive manner through the skindue to the electro-sensitive swelling characteristics of MWCNT/PVA nanocomposite hydrogels.참고 자료
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