colorectal cancer 대장암 발병기전 및 마우스모델 (all 영어)
- 최초 등록일
- 2021.01.14
- 최종 저작일
- 2021.01
- 43페이지/
MS 파워포인트
- 가격 2,500원
목차
1. CRC
1) Definition
2) Incidence
3) Type & Stage
4) Treatment
5) Risk Factors
2. Pathogenesis
1) Chromosomal Instability
2) Microsatellite Instability
3. Mouse Models
1) Chemical Induced Model
2) Genetically Engineered Mouse Model
3) Transplant Model
4) Measurement
4. Recent & Future
1) Humanized mouse
2) Organoid
5. Researches
1) Microbiome & Immunotherapy
본문내용
1. Colorectal Cancer (CRC)
Definition
Disease in which malignant cells form in the tissues of the colon or rectum
Start as a polyps on the inner lining of the colon or rectum
Stage
- Adenocarcinoma (95%)
- Angiosarcoma
- GIST (gastrointestinal stromal tumor)
- Lymphoma
참고 자료
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Mouse models of intestinal cancer. J. Pathol., 238: 141-151. https://doi.org/10.1002/path.4645
The role of mouse models in colorectal cancer research—The need and the importance of the orthotopic models. Animal Model Exp Med. 2020; 3: 1–https://doi.org/10.1002/ame2.12102
The Journal of Medicine and Life Science Vol. 15, No. 2, 42-45, December 2018 https://doi.org/10.22730/jmls.2018.15.2.42 ISSN: 1738-1010
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Korean J Med 79:113-118, 2010
The path to metastatic mouse models of colorectal cancer. Oncogene 37, 2481–2489 (2018). https://doi.org/10.1038/s41388-018-0155-x
Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models. Cells. 2019; 8(8):889.
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The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy. Cancer Cell. 2018 Apr 9;33(4):570-580. doi: 1016/j.ccell.2018.03.015. PMID: 29634945; PMCID: PMC6529202.
The Impact of Intratumoral and Gastrointestinal Microbiota on Systemic Cancer Therapy. Trends Immunol. 2018 Nov;39(11):900-920. doi: 10.1016/j.it.2018.09.007. PMID: 30392721.
