SLE(systemic lupus erythematosus, 전신적 홍반성 낭창) ppt
- 최초 등록일
- 2012.09.19
- 최종 저작일
- 2012.07
- 23페이지/
MS 파워포인트
- 가격 1,000원
소개글
SLE에 대한 모든 내용을 담고 있습니다.
Harrison`s internal medicine 18판을 기본으로 정리하였습니다.
깔끔하고 보기 쉽게 정리한 ppt입니다.
목차
definition
etiology
diagnosis
diagnostic algorithm
clinical manifestation
disease activity
treatment
prognosis
drug-induced lupus
reference
본문내용
Etiology
90% are pregnant woman at the time of diagnosis
Gene polymorphisms : ex. HLA molecules
Female
: Hormone, X chromosome, gender
Environmental stimuli : UV, silica
Infection : EBV
Current tobacco smoking
Diagnosis
D: Discoid rashO: Oral UlcersP: PhotosensitivityA: ArthritisM: Malar rash I : Immunologic disorder (anti-sm, dsDNA, anti-phospholipid)N: Neurologic disorder (psychosis, seizures)ER: Renal disorder (proteinuria>0.5g/d, cellular cast)A: ANA(+)S: Serositis (Pleurisy, pericarditis : EKG, rub, effusion)H: Hematologic (Hemolytic anemia, thrombocytopenia, leukopenia)
Diagnostic algorithm of SLE
Based on clinical features & auto Ab
≥4 /11
Clinical manifestations
Systemic symptoms
: fatigue, myalgia, arthralgia
Musculoskeletal systems
Intermittent polyarthritis
swelling, tenderness
Hands, wrists, knees
참고 자료
Harrison`s Principles of Internal Medicine, 18th edition. P.2724-2735
SELENA INDEX http://www.rheumatology.org/practice/clinical/indexes/sledai.asp
