DNA virus 구조와 특징
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- 2023.04.08
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- 2016.07
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"DNA virus 구조와 특징"에 대한 내용입니다.
목차
1. DNA synthesis by the cellular machinery: Lessons from SV40
2. Mechanisms of viral DNA synthesis
3. Mechanisms of exponential viral DNA synthesis
본문내용
DNA is always synthesized by template-directed, stepwise incorporation of dNMPs into the 3’-OH end of the growing DNA chain, which elongated in the 5’3’ direction
• Each parental strand of a duplex DNA template is copied by base pairing to produce two daughter molecules identical to one another and to their parent: semi- conservative replication
• Replication of DNA begins and ends at specific sites in the template, termed origins and termini, respectively
• DNA synthesis is catalyzed by DNA-dependent DNA polymerases, but many accessory proteins are required for initiation or elongation
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