DMC-induced apoptosis in MG-63 cells was mediated by the expression of Fas and activation of caspase- ... aim of this study was to examine the effects of DMC on cell growth and apoptosis induction in MG-63 human ... These results indicated that DMC inhibits cell proliferation and induces apoptotic cell death in MG-63 human
In this study, hair waste was converted into active carbon for the first time and its characteristics ... As chemical activation tool, zinc chloride ( ZnCl2) was impregnated and then carbonized under different
(MET) and its molecular target in HEp-2 human cervical cancer cells using MTS assay, western blot analysis ... In the present study, we investigated the anti-proliferative activity of methanol extract of tongcao ... we clearly suggest that tongcao can be a potential naturally occurring plants having chemopreventive activity
In this study, we investigated the antibacterial activity of monkey and human origin LABs against monkey ... For non-human primates, homogenous LABs should be used as probiotics, not human origin LABs. ... compared to human origin LABs (p < 0.05).
The present study was designed to investigate the antiproliferative activity and molecular mechanisms ... of Bibimbap in HT-29 human colorectal adenocarcinoma cells. ... Consequently, Bibimbap exerts a significant antiproliferative effect on HT-29 human colorectal adenocarcinoma
Furthermore, Anthricin activates anti-apoptotic factors such as caspase-3, -9 and poly (ADP-ribose) polymerase ... Taken together, these results indicate that Anthricn-induced cell death of human FaDu hypopharyngeal ... We examined the anticancer effect and mechanism of action of Anthricin in human FaDu hypopharyngeal squamous
To investigate whether there are estrogenic and anti-estrogenic activities in various medicinal herbs ... Meyer exhibited inhibitory effects as phytoestrogens in estrogen-responsive human breast cancer cells ... screened and compared the ethanol extracts of 9 plants through the recombinant yeast assay and MCF-7 human
However, it is difficult to obtain this protein in its soluble and active form. hBMP-2 is expressed as ... The refolded recombinant hBMP-2 induced alkaline phosphatase activity in mouse myoblasts, at ED50 of ... combinatorial refolding remarkably enhanced the solubility of the inclusion body, a higher yield of active
In humans, FMO1 appears to be the predominant form expressed in human fetal liver. cDNA-expressed human ... FMO and human liver microsomal FMO have been observed to N- and S-oxygenate nucleophilic nitrogen- and ... Kinetic studies of its S-oxide by recombinant human FMO1 result in K_m of 7.66 μM and V_(max) of 17.79
This study aimed to elucidate the molecular mechanisms of L-AA-induced apoptosis in human laryngeal epidermoid ... Interestingly, L-AA treatment of Hep-2 cells markedly activated Akt and mitogen-activated protein kinase ... In addition, cytochrome c release from the mitochondria into the cytosol and activation of caspase-9,
Growth and differentiation of the human EPO-dependent leukemiae cell line (F36E) were used to measure ... dimeric cDNAs in Chinease hamster ovary (CHO) cells encoding a fusion protein consisting of 2 complete human ... The biological activity and half-life of dHGEPO mutants were enhanced as compared to the corresponding
human, the spermatozoa were treated experimentally and assayed for activities of α-L-fucosidase, α-D-mannosidase ... (p<0.05). β-GlcNAc’ase is present mainly in the plasma membrane of spermatozoa frozen-thawed in human ... To evaluate the effect of spermatozoa culture on glycosidase activity of frozen-thawed spermatozoa in
We conclude therefore that volume activated Cl channels play a putative role in RVD in human salivary ... low Cl bath solution and pharmacological properties suggest that this is a Cα2+ independent, volume activated ... The role of Cl channels in regulatory volume decrease (RVD) in human salivary gland acinar cells was
To analyse the biological activity of the recombinant human EPO (rec-hEPO), we have cloned the EPO cDNA ... The growth and differentiation of EPO-dependent human leukemic cell line (F36E) were used to measure ... These data demonstratethat ree-hEPO produced in this study has a potent activity in vivo and in vitro
of the human body. ... Therefore, these results suggest that the thermostimulation improved immune activity. ... The purpose of this study was to determine the effects of heat appli˗ cation on the immune activities