Bcl-2 family protein plays an important role in the regulation of apoptosis. ... -2 and Bax. ... The regulation of Bcl-2 and Bax proteins by chlorogenic acid during glutamateinduced cell damage were
) while decreasing the expression of Bcl-2 (anti-apoptotic factor). ... -2 family signaling pathway in FaDu human hypopharynx squamous carcinoma cells. ... suggested that latex containing the ficin inhibited cell growth and induced apoptosis by caspase and the Bcl
In addition HS-1200, but not cisplatin, overcomes the anti-apoptotic effects of Bcl-2 in Bcl-2 over-expressing ... human leukemic cells (U937/Bcl-2 cells). ... CBP in the aggregated PML-NBs of U937/Bcl-2 cells.
expressions of the anti-apoptotic Bcl-2 family members (Bcl-2, Bcl-XL, Bcl-W) decreased (p<0.05). ... The pro-survival family members (Bcl-2, Bcl-XL, Bcl-W) are critical for cell survival, since loss of ... The key regulators of apoptosis are the interacting protein of the Bcl-2 family.
Gluvone was associated with down-regulation of anti-apoptotic Bcl-2 protein expression as well as up-regulation ... -2 protein expression. ... mitochondrial dysfunction pathway mediated by enhancement of Bax protein expression and suppression of Bcl
An Apoptotic process was analyzed by a protein expression of the Bcl-2 family using western blotting. ... PineXol® induced a decrease of the Bcl-2 protein expression (p<0.05), while Bax and Sod1 increased ... Rat pheochromocytoma (PC-12) cells were pre-treated with 100 μg/mL of PineXol® for 2 h.
Bcl-2 was observed in LNCaP cells treated with β-glucan. ... -2. ... through the increased of expression caspase-3, -9, Bax, cytochrome C and decreased of expression Bcl
세포사멸의 주요임상지표인 Bax/Bcl-2 ratio는 MDA-MB-231세포에서 가장 유의적으로 증가하였다. ... Moreover the Bax/Bcl-2 ratio of MDA-MB-231 cell was significantly increased as against SK-BR-3, AGS cells ... The level of Bcl-2 decreased, whereas the level of Bax, cleaved-PARP increased in dose-dependent manner
UV irradiation also increased the Bax/Bcl-2 ratio and mitochondrial pathway-associated cytochrome c expression ... Furthermore, the UV irradiationinduced increase in Bax/Bcl-2 ratio, cytochrome c upregulation, and caspase ... , Young Kim, Ok Joon Kim, In-Chol Kang, Won-Jae Kim, Ji-Yeon Jung
, as well as Bax and Bcl-2 expression in dose- and time-dependent manners. ... apoptotic pathway through the modulation of caspase-3, caspase-8, caspase-9, and poly-ADP ribose polymerase ... Analysis of the mechanism of these events showed that Bibimbap-treated cells exhibited a mitochondria-dependent
이는 붉은 토끼풀 추출물이 Caspase-3 비활성, 세포사 촉진단백질 Bax 발현 억제, 세포생존 촉진단백질 Bcl-2 발현 증가 및 MAPK 신호전달계 단백질의 인산화 억제를 통해 ... inhibiting caspase-3 activation, downregulating Bax and upregulating Bcl-2, and attenuating the activation ... Our finding demonstrated that TE effectively protected HaCaT cells against H2O2-induced cell death by
But, for HSG, the increased expression of Bax with decreased of Bcl-2 was observed. ... With the apoptotic machinery study, the Bax and Bcl-2 mRNA expression were not detected in HGF. ... To identify apoptotic cell death, 3-(4,5-dimethylthiazol-2-yl)-2 ,5-diphenyl tetrazolium bromide (MTT
행동평정 프로파일(Behavior Rating Profile-2: BRP-2), 아동기 행동 체크리스트(Child Behavior Checklist: CBCL), 행동장애 종합 선별검사 ... 행동 측정의 일곱 가지 차원 2. ... 청소년 행동평가척도(Korean-Child Behavior Checklist: K-CBCL)가 주로 사용되고 있는 선별도구이다.
배아 줄기 세포에서 YAP1 단백질 안정화를 통해 BCL2L1의 유도를 통해 유사분열 생존을 촉진하는 기전 연구 등을 하고 싶습니다. ... 바이러스 발병을 악화시키는 기전 연구, COP9 신호소체 소단위 5 상호작용을 통한 컬린 데네딜화의 미분 역학 연구, 과산화소체 고환 특이성 1의 BH3 도메인과 복합체를 이루는 Bcl-xL의 ... 프로모터에서 CRL4A-JARID1A를 모집하여 거핵구 분화를 억제하는 기전 연구, SOXE 그룹 전사 인자가 내이 발달 동안 FoxG1의 발현을 조절하는 기전 연구, TPX2가 인간
암세포에서 BCL-2를 억제함에 따라 세포 사멸을 유도합니다. 간단한 기전 세포사멸 과정의 억제는 암세포의 생존과 증식을 위한 핵심 메커니즘입니다. ... 편집: medical writer 연어 특정 암세포에서 과발현된 BCL-2는 세포사멸 촉진 단백질의 결합을 방해함으로써, 암세포가 세포사멸하는 것을 피할 수 있게 합니다. ... 편집: medical writer 연어 여기서 벤클렉스타정을 투여하게되면, BCL-2를 무력화시켜, 세포사멸 촉진단백질이 암세포와 결합할 수 있도록 유도하고, 그 결과 암세포가 사멸됩니다
Bilobalide significantly increased Bax/Bcl-2 ratio. ... Immunoblotting revealed that the antiapoptotic mitochondrial protein Bcl-2 was downregulated, but the ... This was examined by 3-[4,5-dimethylthiazol-2-yl]-2,5- diphenyltetrazolium bromide assay, nuclear 4′,
학문적 지향 저는 국내 경증 천식 소아에서 부데소니드 흡입 현탁액과 몬테루카스트의 비교 효과 분석 연구, 새로운 Bcl-2 계열 구성원으로서 인간 Bfk의 세포사멸 조절에 대한 구조적 ... , IL-5, IL-3 및 GM-CSF와 같은 Th2 사이토카인을 표적으로 하는 항알레르기 반응 및 작용 메커니즘 연구, 환자의 복약 경험을 위한 환자 중심 웹 포털의 의료 적용 가능성 ... 저는 약학과 학부 때 약학기초화학1, 해부생리학, 의약품분석학1, 약학실험1, 물리약학1,2, 조제학, 일반의약품학, 종양생물학, 약학통계 등의 수업을 수강했습니다. 2.