Expression of SREPB-1α, SREPB-2 mRNA in the liver was lower in the high-fat diet group compared with ... of PPAR-1α and SREPB-2 mRNA and the up-regulation of PPAR-α mRNA. ... Triglyceride, total cholesterol, LDL-C and AI decreased in HFD 15 and HFD 30 groups compared with in
, by regulating cholesterol metabolism-related biochemical parameters and SREBP-1⍺ SREPB-2 and PPAR⍺gene ... EM은 고콜레스테롤 식이를 공급받은 랫드의 간에서 SREBP-1α, SREBP-2 mRNA 발현을 억압함과 동시에 PPARα mRNA 발현을 촉진시키는 것으로 나타났다 (p<0.05 ... It was discovered that EM suppress the expression of SREBP-1⍺and SREBP-2 mRNA in the liver tissues of