Can vitamin C and interleukin 6 levels predict preterm premature rupture of membranes: evaluating possibilities in North Indian population

최초 등록일
2020.08.13
최종 저작일
2020.08
8페이지/파일확장자 어도비 PDF
가격 4,000원 할인쿠폰받기
판매자한국학술정보(주)
다운로드
장바구니
자격시험 기출문제풀이 - 서비스 오픈 이벤트

* 본 문서는 배포용으로 복사 및 편집이 불가합니다.

서지정보

발행기관 : 대한산부인과학회 수록지정보 : Obstetrics & Gynecology Science / 63권 / 4호
저자명 : ( Sumedha Gupta ) , ( Harsha S. Gaikwad ) , ( Banashree Nath ) , ( Achla Batra¸ Dgo )

영어 초록

ObjectiveWe aimed to evaluate the relation between plasma ascorbic acid levels and the occurrence of preterm premature rupture of membranes (PPROM) and whether patients with ascorbic acid deficiency have predisposition to microbial invasion, as revealed by serum interleukin-6 (IL-6) levels and confirmed by placental culture sensitivity evaluation.MethodsThis controlled study involved 50 women with PPROM at gestational age between 28 and 36.6 weeks. Fifty patients with uncomplicated pregnancy and intact membranes were observed as control group. Serum ascorbic acid and IL-6 levels were evaluated for PPROM group subjects and controls, matched by their gestational age and body mass index. Repeat samples for IL-6 were taken after 48 hours of admission in PROM group subjects and at the onset of labor in controls. Placental membranes were sent for culture sensitivity evaluation after delivery.ResultsThe mean plasma level of ascorbic acid was 0.60±0.35 mg/dL and 1.18±0.43 mg/dL in the PPROM and control groups, respectively, showing significant difference. Plasma IL-6 level rose from 18.18±5.94 pg/mL to 34.32±7.31 pg/mL after 48 hours of admission in the PPROM group (P=0.000). Plasma IL-6 level in controls rose from 5.59±4.36 pg/mL at admission to 7.36±3.67 pg/mL at the onset of labor. Membrane culture test results were positive in a total of 40 samples, of which 37 samples were from the PPROM group subjects.ConclusionVitamin C deficiency, when complemented with elevated serum IL-6 level, can predict susceptibility to PPROM in the third trimester; the risk increases in women with prior history of similar pathology.

참고 자료

없음

자료문의

제휴사는 별도로 자료문의를 받지 않고 있습니다.

판매자 정보

한국학술정보(주)는 콘텐츠 제작에 도움이 되는 솔루션을 기반으로 풍부한 문화 콘텐츠를 생성하여 새로운 삶의 가치를 창조합니다.

본 학술논문은 한국학술정보(주)와 각 학회간에 저작권계약이 체결된 것으로 AgentSoft가 제공 하고 있습니다.
본 저작물을 불법적으로 이용시는 법적인 제재가 가해질 수 있습니다.

찾던 자료가 아닌가요?아래 자료들 중 찾던 자료가 있는지 확인해보세요

더보기
상세하단 배너
우수 콘텐츠 서비스 품질인증 획득
최근 본 자료더보기
Can vitamin C and interleukin 6 levels predict preterm premature rupture of membranes: evaluating possibilities in North Indian population