Background and Aim:This study was aimed to compare perinatal outcome between different latency time among women with late preterm premature rupture of membranes (PPROM).Methods:This retrospective case-control study included women with PPROM from 34+0 to 36+6 weeks of gestation, who delivered at Korea University Hospital in Ansan from Jan. 2006 to Dec. 2017. The maternal characteristics, neonatal characteristics and neonatal outcome variables were compared between different latency times (>72h versus ≤72h). Women who delivered within two hours, who diagnosed fetal congenital anomalies and not delivered in our institution were excluded from this study.Result:A total of two hundred fifty women with late PPROM were analyzed. There were thirty PPROM women with latency >72h. There were no significant differences between two groups in gestational age at delivery, oligohydramnios (AFI<5), and histologic chorioamnionitis. Women with latency ≤72h had more short cervical length (<2.5cm) (p< 0.001) and experienced more cesarean delivery (p=0.02). Neonatal outcomes (5min Apgar score less than 7, ventilator care, sepsis, NEC, RDS, PVL, BPD, IVH grade 3 to 4 and neonatal death) demonstrated no significant difference between two groups.Conclusion:In women with late PPROM, latency time >72h did not result in increased adverse neonatal outcome compared to latency time ≤72h. This finding may be helpful for optimizing maternal and neonatal care in women with late PPROM.